| Literature DB >> 9871777 |
B Bellier1, S Da Nascimento, H Meudal, E Gincel, B P Roques, C Garbay.
Abstract
A new series of 4-substituted pipecolic acid derivatives was prepared and incorporated into dipeptoids. The resulting products behave as moderately potent CCK-B antagonists but their constrained structure and its comparison with structurally related compounds yield valuable information about the conformational requirements for optimal recognition of the CCK-B receptor by antagonists.Entities:
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Year: 1998 PMID： 9871777 DOI： 10.1016/s0960-894x(98)00231-5
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823