| Literature DB >> 9871769 |
B Cimetière1, T Dubuffet, O Muller, J J Descombes, S Simonet, M Laubie, T J Verbeuren, G Lavielle.
Abstract
New polysubstituted tetrahydronaphthalene derivatives were prepared as thromboxane receptor (TP-receptor) antagonists. Within this series of compounds S 18886 has been identified as an orally active, highly potent antagonist with a very long duration of action in different species.Entities:
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Year: 1998 PMID: 9871769 DOI: 10.1016/s0960-894x(98)00220-0
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823