Literature DB >> 9871757

Design and synthesis of isoxazole and isoxazoline linkage for replacement of nucleotide phosphodiester.

S J Kim1, J Y Lee, B H Kim.   

Abstract

Synthetic routes for oligonucleotides which have isoxazoline or isoxazole linkage have been developed, and di- and tri-nucleotides with thymine bases have been prepared.

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Year:  1998        PMID： 9871757     DOI： 10.1016/s0960-894x(98)00210-8

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  1 in total

1.  Synthesis of 5-isoxazol-5-yl-2'-deoxyuridines exhibiting antiviral activity against HSV and several RNA viruses.

Authors:  Yoon-Suk Lee; Sun Min Park; Byeang Hyean Kim
Journal:  Bioorg Med Chem Lett       Date:  2008-12-31       Impact factor: 2.823
  1 in total

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