Literature DB >> 9871698

Complexation of okadaic acid: a preliminary study.

M Norte1, J J Fernández, M L Souto, J A Gavín, M L Candenas, P Ausina.   

Abstract

A complexation study was carried out with okadaic acid (OA) and the univalent metal ions Li+, Na+ and K+, and the divalent metal ions Ca2+ and Mg2+. K+ binding was observed identical with a complex obtained from the natural source (OAC). The pharmacological trials demonstrated that this cation has a very important influence on the pharmacological activity of okadaic acid.

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Year:  1998        PMID： 9871698     DOI： 10.1016/s0960-894x(98)00152-8

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  High-Throughput Screening of a Marine Compound Library Identifies Anti-Cryptosporidium Activity of Leiodolide A.

Authors:  Rachel M Bone Relat; Priscilla L Winder; Gregory D Bowden; Esther A Guzmán; Tara A Peterson; Shirley A Pomponi; Jill C Roberts; Amy E Wright; Roberta M O'Connor
Journal:  Mar Drugs       Date:  2022-03-30       Impact factor: 6.085

2.  Self-association of okadaic acid: structural and pharmacological significance.

Authors:  Patricia G Cruz; Manuel Norte; Alberto Hernández Creus; José J Fernández; Antonio Hernández Daranas
Journal:  Mar Drugs       Date:  2013-05-29       Impact factor: 5.118
  2 in total

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