Literature DB >> 9871655

Stereochemistry of the reduction of 24-ethyldesmosterol to sitosterol in tissue cultures of Oryza sativa.

Y Fujimoto1, N Sato, T Okuzumi, J Yamada, M Morisaki.   

Abstract

Feeding of [26-13C]- and [27-13C]-24-ethyldesmosterols to cultured cells of Oryza sativa followed by 13C-NMR analysis of the biosynthesized sitosterol revealed that the reduction of 24(25)-double bond proceeds with an anti-addition of hydrogen atoms, thus the E-methyl group of the olefinic precursor becomes the pro-S-methyl on C-25 of sitosterol.

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Year:  1998        PMID: 9871655     DOI: 10.1016/s0960-894x(97)10220-7

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  Ajuga Δ24-Sterol Reductase Catalyzes the Direct Reductive Conversion of 24-Methylenecholesterol to Campesterol.

Authors:  Yuki Tsukagoshi; Hideyuki Suzuki; Hikaru Seki; Toshiya Muranaka; Kiyoshi Ohyama; Yoshinori Fujimoto
Journal:  J Biol Chem       Date:  2016-02-12       Impact factor: 5.157

Review 2.  Biosynthesis of cholesterol and other sterols.

Authors:  W David Nes
Journal:  Chem Rev       Date:  2011-09-08       Impact factor: 60.622

  2 in total

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