| Literature DB >> 9871650 |
Abstract
Ceramides are the major lipid components of the stratum corneum, the major permeability barrier of the skin. Here we report a chemical synthesis of ceramide analogs covalently bonded on the silica particles, that can be used to predict the skin permeability of chemicals via HPLC methods.Entities:
Mesh：
Substances：
Year: 1998 PMID： 9871650 DOI： 10.1016/s0960-894x(97)10217-7
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823