Literature DB >> 9871643

Synthesis and immunosuppressive activity of ruthenium complexes.

C M Bastos1, K A Gordon, T D Ocain.   

Abstract

The syntheses and immunosuppressive activity of ruthenium complexes are described. One of the complexes (1a) was shown to be a potent inhibitor of human T-lymphocyte proliferation with an IC50 of 5 nM. The activity of these complexes compares favorably to the well known immunosuppressants Cyclosporin A and Rapamycin.

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Year:  1998        PMID： 9871643     DOI： 10.1016/s0960-894x(97)10205-0

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

1.  In vitro effects of binuclear (η (6)-p-cymene)ruthenium(II) complex containing bridging bis(nicotinate)-polyethylene glycol ester ligand on differentiation pathways of murine Th lymphocytes activated by T cell mitogen.

Authors:  Miljana Momcilovic; Thomas Eichhorn; Jana Blazevski; Harry Schmidt; Goran N Kaluđerović; Stanislava Stosic-Grujicic
Journal:  J Biol Inorg Chem       Date:  2015-02-10       Impact factor: 3.358

Review 2.  Recent Advances in Schiff Base Ruthenium Metal Complexes: Synthesis and Applications.

Authors:  Anmol Singh; Pranjit Barman
Journal:  Top Curr Chem (Cham)       Date:  2021-06-10

3.  Proton Conduction at High Temperature in High-Symmetry Hydrogen-Bonded Molecular Crystals of RuIII Complexes with Six Imidazole-Imidazolate Ligands.

Authors:  Makoto Tadokoro; Masaki Itoh; Ryota Nishimura; Kensuke Sekiguchi; Norihisa Hoshino; Hajime Kamebuchi; Jun Miyazaki; Fumiya Kobayashi; Motohiro Mizuno; Tomoyuki Akutagawa
Journal:  Chemistry       Date:  2022-07-26       Impact factor: 5.020
  3 in total

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