| Literature DB >> 9871641 |
R E Armer1, C J Dutton, B R Fenner, S D Greenwood, K T Hall, A J Rudge.
Abstract
Carbocyclic analogues of the antibacterial natural product frenolicin B have been synthesised. These analogues were active against parasitic protozoa of the genus Eimeria and represent a new series of anticoccidial agents. The synthesis of simplified analogues helped to define a possible pharmacophore for frenolicin.Entities:
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Year: 1998 PMID: 9871641 DOI: 10.1016/s0960-894x(97)10200-1
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823