| Literature DB >> 9871626 |
D A Neel1, M R Jirousek, J H McDonald.
Abstract
Bisindolylmaleimides are known to be potent and selective PKC inhibitors. A new synthesis of this class of compound is reported. The key step is a Suzuki cross-coupling reaction using a readily available indolylmaleimide triflate intermediate.Entities:
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Year: 1998 PMID： 9871626 DOI： 10.1016/s0960-894x(97)10174-3
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823