| Literature DB >> 987157 |
Abstract
Baby hamster kidney cells were persistently infected with lymphocytic choriomeningitis (LCM) virus (BHKpi cells). After 21 passages of the BHKpi cells infectious virus could no longer be detected; however, the cultures continued to produce LCM virus particles which interfered with the replication of infectious LCM virus in BHKpi cells and protected mice from a subsequent intracranial inoculation of infectious LCM virus. Cultures of BHKpi cells appeared to consist of three cell populations: uninfected cells, infected cells containing infectious LCM virus, and infected cells releasing interfering particles of LCM virus.Entities:
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Year: 1976 PMID： 987157 DOI： 10.1099/0022-1317-32-3-361
Source DB: PubMed Journal: J Gen Virol ISSN： 0022-1317 Impact factor: 3.891