| Literature DB >> 9871565 |
V L Novikov, O B Maximov, G B Elyakov, D O Levitsky, A V Lebedev, S M Sadretdinov, A V Shvilkin, N I Afonskaya, N M Cherpachenko.
Abstract
A series of hydroxynaphthazarins has been synthesized. Some of them were found in in vivo experiments to be protectors of myocardium under ischemia-reperfusion and to reduce the infarction zone by 50% without any adverse effect. All compounds exhibit a moderate or small toxicity and are active in low doses.Entities:
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Year: 1998 PMID： 9871565 DOI： 10.1016/s0960-894x(98)00075-4
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823