| Literature DB >> 9871560 |
K Ishibashi1, K Nakajima, Y Sugioka, M Sugiyama, T Hamada, H Horikoshi, T Nishi.
Abstract
A series of 2-phenylbenzofuran derivatives with a diphenylmethylcarbamoyl group at the 5 or 6 position of the benzofuran ring were synthesized and evaluated for rat and human testosterone 5 alpha-reductase inhibitory activities in vitro. They had inhibitory activities against both enzymes and the 6-carbamoyl derivatives tended to be more potent than the 5-carbamoyl compounds.Entities:
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Year: 1998 PMID： 9871560 DOI： 10.1016/s0960-894x(98)00001-8
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823