Literature DB >> 9871519

Phthalimidomethyl as a drug pro-moiety. Probing its reactivity.

J Iley1, T Calheiros, R Moreira.   

Abstract

Phthalimidomethyl derivatives 1, encompassing a wide range of leaving group abilities, are rapidly hydrolysed to the corresponding phthalamic acid via rate-determining attack at the phthalimide carbonyl group.

Entities:  

Mesh:

Substances:

Year:  1998        PMID: 9871519     DOI: 10.1016/s0960-894x(98)00135-8

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  Study on Photophysical Properties of N-Arylphthalamic Acid Derivative Containing 1, 2, 4-Triazole Scaffold.

Authors:  K B Akshaya; Anitha Varghese; Y N Sudhakar; Prajwal Lourdes Lobo; Louis George
Journal:  J Fluoresc       Date:  2017-06-21       Impact factor: 2.217

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.