Literature DB >> 9869587

Experimental evaluation of second-line oral treatments of visceral leishmaniasis caused by Leishmania infantum.

J P Gangneux1, M Dullin, A Sulahian, Y J Garin, F Derouin.   

Abstract

In a murine model of Leishmania infantum visceral leishmaniasis, metronidazole, ketoconazole, fluconazole, itraconazole, and terbinafine were less effective than antimonial agents in reducing hepatic parasite load. Ketoconazole potentiated the effect of meglumine antimoniate reference therapy through its marked activity against spleen infection.

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Year:  1999        PMID： 9869587      PMCID： PMC89042     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  30 in total

1.  Maintenance itraconazole for visceral leishmaniasis in HIV infection.

Authors:  A Lafeuillade; P Chaffanjon; E Delbeke; R Quilichini
Journal:  Am J Med       Date:  1992-04       Impact factor: 4.965

2.  Efficacy of aminosidine administered alone or in combination with meglumine antimoniate for the treatment of experimental visceral leishmaniasis caused by Leishmania infantum.

Authors:  J P Gangneux; A Sulahian; Y J Garin; F Derouin
Journal:  J Antimicrob Chemother       Date:  1997-08       Impact factor: 5.790

3.  Failure to cure Leishmania braziliensis guyanensis cutaneous leishmaniasis with oral ketoconazole.

Authors:  J P Dedet; P Jamet; P Esterre; P M Ghipponi; C Genin; G Lalande
Journal:  Trans R Soc Trop Med Hyg       Date:  1986       Impact factor: 2.184

Review 4.  Human leishmaniasis: clinical, diagnostic, and chemotherapeutic developments in the last 10 years.

Authors:  J D Berman
Journal:  Clin Infect Dis       Date:  1997-04       Impact factor: 9.079

5.  Efficacy of ketoconazole against Leishmania braziliensis panamensis cutaneous leishmaniasis.

Authors:  R E Saenz; H Paz; J D Berman
Journal:  Am J Med       Date:  1990-08       Impact factor: 4.965

6.  Visceral leishmaniasis: drug carrier system characteristics and the ability to clear parasites from the liver, spleen and bone marrow in Leishmania donovani infected BALB/c mice.

Authors:  K C Carter; T F Dolan; J Alexander; A J Baillie; C McColgan
Journal:  J Pharm Pharmacol       Date:  1989-02       Impact factor: 3.765

7.  Inefficacy of ethambutol, ethambutol plus isoniazid, INH plus rifampicin, co-trimoxazole and metronidazole in the treatment of kala-azar.

Authors:  C P Thakur; P K Sinha
Journal:  J Trop Med Hyg       Date:  1989-12

8.  Mechanism of amphotericin B resistance in Leishmania donovani promastigotes.

Authors:  N Mbongo; P M Loiseau; M A Billion; M Robert-Gero
Journal:  Antimicrob Agents Chemother       Date:  1998-02       Impact factor: 5.191

9.  Failure of oral ketoconazole to cure cutaneous ulcers caused by Leishmania braziliensis.

Authors:  M Dan; E Verner; J el-On; F Zuckerman; D Michaeli
Journal:  Cutis       Date:  1986-09

10.  Placebo-controlled clinical trial of sodium stibogluconate (Pentostam) versus ketoconazole for treating cutaneous leishmaniasis in Guatemala.

Authors:  T R Navin; B A Arana; F E Arana; J D Berman; J F Chajón
Journal:  J Infect Dis       Date:  1992-03       Impact factor: 5.226
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  15 in total

Review 1.  Clinical and experimental advances in treatment of visceral leishmaniasis.

Authors:  H W Murray
Journal:  Antimicrob Agents Chemother       Date:  2001-08       Impact factor: 5.191

2.  Clinical efficacy of two different drug combinations for the treatment of canine leishmaniasis.

Authors:  M G Pennisi; S Lo Giudice; M Masucci; M De Majo; S Reale; F Vitale
Journal:  Vet Res Commun       Date:  2008-09       Impact factor: 2.459

3.  Use of terbinafine in mouse and rat models of Pneumocystis carinii pneumonia.

Authors:  Peter D Walzer; Alan Ashbaugh
Journal:  Antimicrob Agents Chemother       Date:  2002-02       Impact factor: 5.191

4.  Antileishmanial Efficacy and Pharmacokinetics of DB766-Azole Combinations.

Authors:  April C Joice; Sihyung Yang; Abdelbasset A Farahat; Heidi Meeds; Mei Feng; Junan Li; David W Boykin; Michael Zhuo Wang; Karl A Werbovetz
Journal:  Antimicrob Agents Chemother       Date:  2017-12-21       Impact factor: 5.191

5.  Effect of Itraconazole-Ezetimibe-Miltefosine Ternary Therapy in Murine Visceral Leishmaniasis.

Authors:  Valter V Andrade-Neto; Karina M Rebello; Thais M Pereira; Eduardo Caio Torres-Santos
Journal:  Antimicrob Agents Chemother       Date:  2021-02-22       Impact factor: 5.191

6.  Alkyl galactofuranosides strongly interact with Leishmania donovani membrane and provide antileishmanial activity.

Authors:  Muhammad Suleman; Jean-Pierre Gangneux; Laurent Legentil; Sorya Belaz; Yari Cabezas; Christelle Manuel; Rémy Dureau; Odile Sergent; Agnès Burel; Franck Daligault; Vincent Ferrières; Florence Robert-Gangneux
Journal:  Antimicrob Agents Chemother       Date:  2014-01-27       Impact factor: 5.191

7.  The efficacy of enrofloxacin, alone or combined with metronidazole, in the therapy of canine leishmaniasis.

Authors:  Paolo Bianciardi; Antonio Fasanella; Valentina Foglia Manzillo; Teresa Trotta; Annalisa Pagano; Simona Sorino; Luigi Gradoni; Gaetano Oliva
Journal:  Parasitol Res       Date:  2004-07-23       Impact factor: 2.289

8.  Antileishmanial Activity of Ezetimibe: Inhibition of Sterol Biosynthesis, In Vitro Synergy with Azoles, and Efficacy in Experimental Cutaneous Leishmaniasis.

Authors:  Valter Viana Andrade-Neto; Edézio Ferreira Cunha-Júnior; Marilene Marcuzzo do Canto-Cavalheiro; Geórgia Correa Atella; Talita de Almeida Fernandes; Paulo Roberto Ribeiro Costa; Eduardo Caio Torres-Santos
Journal:  Antimicrob Agents Chemother       Date:  2016-10-21       Impact factor: 5.191

9.  Dihydrobetulinic acid induces apoptosis in Leishmania donovani by targeting DNA topoisomerase I and II: implications in antileishmanial therapy.

Authors:  Arnab Roy Chowdhury; Suparna Mandal; Anindya Goswami; Monidipa Ghosh; Labanya Mandal; Debabani Chakraborty; Agneyo Ganguly; Gayatri Tripathi; Sibabrata Mukhopadhyay; Santu Bandyopadhyay; Hemanta K Majumder
Journal:  Mol Med       Date:  2003 Jan-Feb       Impact factor: 6.354

10.  Voriconazole suppresses the growth of Leishmania species in vitro.

Authors:  Manjusha M Kulkarni; Niveditha Reddy; Tulasi Gude; Bradford S McGwire
Journal:  Parasitol Res       Date:  2013-02-08       Impact factor: 2.289
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