Literature DB >> 9869111

DNA vaccines: application to tuberculosis.

K Huygen1.   

Abstract

Since the first observations in the early 1990s, the scientific literature on DNA vaccines has been growing exponentially. This article reviews the history and general principle, summarizes current knowledge on immune mechanisms, discusses safety considerations and highlights possible advantages of this technique as compared to the classic vaccines. Special emphasis is placed on the potential of DNA vaccines with respect to tuberculosis.

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Year:  1998        PMID： 9869111

Source DB:  PubMed          Journal:  Int J Tuberc Lung Dis        ISSN： 1027-3719            Impact factor:   2.373


  12 in total

1.  Immunogenicity of DNA vaccines expressing tuberculosis proteins fused to tissue plasminogen activator signal sequences.

Authors:  Z Li; A Howard; C Kelley; G Delogu; F Collins; S Morris
Journal:  Infect Immun       Date:  1999-09       Impact factor: 3.441

2.  Tuberculosis DNA vaccine encoding Ag85A is immunogenic and protective when administered by intramuscular needle injection but not by epidermal gene gun bombardment.

Authors:  A Tanghe; O Denis; B Lambrecht; V Motte; T van den Berg; K Huygen
Journal:  Infect Immun       Date:  2000-07       Impact factor: 3.441

3.  Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccination.

Authors:  Joshua S Woodworth; Daniel Shin; Mattijs Volman; Cláudio Nunes-Alves; Sarah M Fortune; Samuel M Behar
Journal:  J Immunol       Date:  2010-12-22       Impact factor: 5.422

4.  Lack of protection in mice and necrotizing bronchointerstitial pneumonia with bronchiolitis in guinea pigs immunized with vaccines directed against the hsp60 molecule of Mycobacterium tuberculosis.

Authors:  O C Turner; A D Roberts; A A Frank; S W Phalen; D M McMurray; J Content; O Denis; S D'Souza; A Tanghe; K Huygen; I M Orme
Journal:  Infect Immun       Date:  2000-06       Impact factor: 3.441

5.  DNA vaccination with genes encoding Toxoplasma gondii antigens GRA1, GRA7, and ROP2 induces partially protective immunity against lethal challenge in mice.

Authors:  M Vercammen; T Scorza; K Huygen; J De Braekeleer; R Diet; D Jacobs; E Saman; H Verschueren
Journal:  Infect Immun       Date:  2000-01       Impact factor: 3.441

6.  Preclinical study and clinical trial of a novel therapeutic vaccine against multi-drug resistant tuberculosis.

Authors:  Masaji Okada; Yoko Kita; Satomi Hashimoto; Hitoshi Nakatani; Shiho Nishimastu; Yumiko Kioka; Yasuko Takami
Journal:  Hum Vaccin Immunother       Date:  2016-12-14       Impact factor: 3.452

7.  Novel therapeutic vaccines [(HSP65 + IL-12)DNA-, granulysin- and Ksp37-vaccine] against tuberculosis and synergistic effects in the combination with chemotherapy.

Authors:  Yoko Kita; Satomi Hashimoto; Toshihiro Nakajima; Hitoshi Nakatani; Shiho Nishimatsu; Yasuko Nishida; Noriko Kanamaru; Yasuhumi Kaneda; Yasushi Takamori; David McMurray; Esterlina V Tan; Marjorie L Cang; Paul Saunderson; E C Dela Cruz; Masaji Okada
Journal:  Hum Vaccin Immunother       Date:  2012-12-18       Impact factor: 3.452

8.  Improved tuberculosis DNA vaccines by formulation in cationic lipids.

Authors:  S D'Souza; V Rosseels; O Denis; A Tanghe; N De Smet; F Jurion; K Palfliet; N Castiglioni; A Vanonckelen; C Wheeler; K Huygen
Journal:  Infect Immun       Date:  2002-07       Impact factor: 3.441

9.  Novel prophylactic vaccine using a prime-boost method and hemagglutinating virus of Japan-envelope against tuberculosis.

Authors:  Masaji Okada; Yoko Kita; Toshihiro Nakajima; Noriko Kanamaru; Satomi Hashimoto; Tetsuji Nagasawa; Yasufumi Kaneda; Shigeto Yoshida; Yasuko Nishida; Hitoshi Nakatani; Kyoko Takao; Chie Kishigami; Shiho Nishimatsu; Yuki Sekine; Yoshikazu Inoue; David N McMurray; Mitsunori Sakatani
Journal:  Clin Dev Immunol       Date:  2011-03-07

10.  A Novel Therapeutic and Prophylactic Vaccine against Tuberculosis Using the Cynomolgus Monkey Model and Mouse Model.

Authors:  M Okada; Y Kita; T Nakajima; N Kanamaru; Y Kaneda; P Saunderson; E V Tan; D N McMurray
Journal:  Procedia Vaccinol       Date:  2011-09-29
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