Literature DB >> 9868546

Topoisomerase I inhibitors from the Streptomyces sp. strain KM86-9B isolated from a marine sponge.

H K Lee1, D S Lee, J Lim, J S Kim, K S Im, J H Jung.   

Abstract

The crude extract of Streptomyces sp. strain KM86-9B, isolated from a marine sponge, displayed significant inhibition on topoisomerase I activity. Investigation of the causative components by bioactivity-directed fractionation resulted in the isolation of a series of iso- and anteiso-fatty acids.

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Year:  1998        PMID: 9868546     DOI: 10.1007/bf02976766

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN: 0253-6269            Impact factor:   4.946


  7 in total

1.  First total synthesis and antileishmanial activity of (Z)-16-methyl-11-heptadecenoic acid, a new marine fatty acid from the sponge Dragmaxia undata.

Authors:  Néstor M Carballeira; Nashbly Montano; Gabriel A Cintrón; Carmary Márquez; Celia Fernández Rubio; Christopher Fernández Prada; Rafael Balaña-Fouce
Journal:  Chem Phys Lipids       Date:  2010-12-01       Impact factor: 3.329

2.  First total syntheses of (Z)-15-methyl-10-hexadecenoic acid and the (Z)-13-methyl-8-tetradecenoic acid.

Authors:  Néstor M Carballeira; Nashbly Montano; Luis F Padilla
Journal:  Chem Phys Lipids       Date:  2006-11-13       Impact factor: 3.329

Review 3.  Antitumor compounds from marine actinomycetes.

Authors:  Carlos Olano; Carmen Méndez; José A Salas
Journal:  Mar Drugs       Date:  2009-06-11       Impact factor: 5.118

4.  Isolation, phylogenetic analysis and anti-infective activity screening of marine sponge-associated actinomycetes.

Authors:  Usama Ramadan Abdelmohsen; Sheila M Pimentel-Elardo; Amro Hanora; Mona Radwan; Soad H Abou-El-Ela; Safwat Ahmed; Ute Hentschel
Journal:  Mar Drugs       Date:  2010-02-26       Impact factor: 5.118

Review 5.  Mechanism targeted discovery of antitumor marine natural products.

Authors:  Dale G Nagle; Yu-Dong Zhou; Flor D Mora; Kaleem A Mohammed; Yong-Pil Kim
Journal:  Curr Med Chem       Date:  2004-07       Impact factor: 4.530

Review 6.  New advances in fatty acids as antimalarial, antimycobacterial and antifungal agents.

Authors:  N M Carballeira
Journal:  Prog Lipid Res       Date:  2007-11-01       Impact factor: 16.195

7.  An improved synthesis for the (Z)-14-methyl-9-pentadecenoic acid and its topoisomerase I inhibitory activity.

Authors:  Néstor M Carballeira; David Sanabria; Delise Oyola
Journal:  ARKIVOC       Date:  2007       Impact factor: 1.140

  7 in total

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