| Literature DB >> 9868149 |
A F Barrero1, J E Oltra, J A Poyatos, D Jiménez, E Oliver.
Abstract
In the search for novel bioactive products from filamentous fungi, sterols and triterpenoids found in Phycomyces blakesleeanus were analyzed using semipreparative HPLC, GC-MS, and NMR techniques. Structures proposed for the three new compounds identified, phycomysterol A (1), phycomysterol B (2), and neoergosterol (3), were confirmed by chemical synthesis. Phycomysterols possess a new natural 19-norergostane skeleton with an aromatic B ring. Phycomysterol A showed anti-HIV activity.Entities:
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Year: 1998 PMID： 9868149 DOI： 10.1021/np980199h
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050