| Literature DB >> 9866734 |
C B Beard1, R V Durvasula, F F Richards.
Abstract
Bacterial symbionts may be used as vehicles for expressing foreign genes in arthropods. Expression of selected genes can render an arthropod incapable of transmitting a second microorganism that is pathogenic for humans and is an alternative approach to the control of arthropod-borne diseases. We discuss the rationale for this alternative approach, its potential applications and limitations, and the regulatory concerns that may arise from its use in interrupting disease transmission in humans and animals.Entities:
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Year: 1998 PMID: 9866734 PMCID: PMC2640264 DOI: 10.3201/eid0404.980408
Source DB: PubMed Journal: Emerg Infect Dis ISSN: 1080-6040 Impact factor: 6.883