Literature DB >> 9865630

Evaluation of gastroesophageal reflux in patients with laryngotracheal stenosis.

R J Toohill1, S O Ulualp, R Shaker.   

Abstract

To report the incidence of pharyngeal acid reflux events in patients with laryngotracheal stenosis (LTS), we studied 12 patients with LTS and 34 healthy volunteers. All patients and controls underwent ambulatory 24-hour 3-site pH monitoring. In ambulatory pH monitoring, pH was recorded at manometrically determined sites of the pharynx, proximal esophagus, and distal esophagus. For all 3 sites, a pH value below 4 that was not related to the time of oral intake or belching was considered an acid reflux event. Eight of the 12 LTS patients exhibited pharyngeal acid reflux events. In the control group, pharyngeal acid reflux events were documented in 7 subjects. In between-group comparison, the number of reflux episodes and the percent acid exposure time in the pharynx were greater in LTS patients than in controls. Reflux parameters of the proximal and distal esophagus in LTS patients were similar to those of controls. The incidence of pharyngeal acid reflux events in LTS patients was higher than that in controls. It is suggested that identification and treatment of gastroesophageal reflux in patients will significantly simplify and improve the results of treatment for LTS.

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Year:  1998        PMID: 9865630     DOI: 10.1177/000348949810701203

Source DB:  PubMed          Journal:  Ann Otol Rhinol Laryngol        ISSN: 0003-4894            Impact factor:   1.547


  4 in total

1.  [Laryngopharyngeal reflux: change in paradigm or diagnostic catchall?].

Authors:  C Sittel
Journal:  HNO       Date:  2003-09       Impact factor: 1.284

2.  Laryngopharyngeal reflux symptoms better predict the presence of esophageal adenocarcinoma than typical gastroesophageal reflux symptoms.

Authors:  Kevin M Reavis; Cynthia D Morris; Deepak V Gopal; John G Hunter; Blair A Jobe
Journal:  Ann Surg       Date:  2004-06       Impact factor: 12.969

Review 3.  The "forgotten zone": acquired disorders of the trachea in adults.

Authors:  Mazen O Al-Qadi; Andrew W Artenstein; Sidney S Braman
Journal:  Respir Med       Date:  2013-05-10       Impact factor: 3.415

Review 4.  Impact of gastroesophageal reflux in the pathogenesis of tracheal stenosis.

Authors:  Paulo Francisco Guerreiro Cardoso; Helio Minamoto; Benoit Jacques Bibas; Paulo Manuel Pego-Fernandes
Journal:  Transl Cancer Res       Date:  2020-03       Impact factor: 1.241

  4 in total

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