Literature DB >> 9865537

Carbachol, an acetylcholine receptor agonist, enhances production in rat aorta of 2-arachidonoyl glycerol, a hypotensive endocannabinoid.

R Mechoulam1, E Fride, S Ben-Shabat, U Meiri, M Horowitz.   

Abstract

The production of 2-arachidonoyl glycerol, an endogenous cannabinoid, is enhanced in normal, but not in endothelium-denuded rat aorta on stimulation with carbachol, an acetylcholine receptor agonist. 2-Arachidonoyl glycerol potently reduces blood pressure in rats and may represent an endothelium-derived hypotensive factor.

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Year:  1998        PMID： 9865537     DOI： 10.1016/s0014-2999(98)00777-8

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  20 in total

Review 1.  Regulation of endocannabinoid release by G proteins: a paracrine mechanism of G protein-coupled receptor action.

Authors:  Pál Gyombolai; Dorottya Pap; Gábor Turu; Kevin J Catt; György Bagdy; László Hunyady
Journal:  Mol Cell Endocrinol       Date:  2011-11-02       Impact factor: 4.102

Review 2.  The complexities of the cardiovascular actions of cannabinoids.

Authors:  Michael D Randall; David A Kendall; Saoirse O'Sullivan
Journal:  Br J Pharmacol       Date:  2004-05       Impact factor: 8.739

Review 3.  Endocannabinoids in cerebrovascular regulation.

Authors:  Zoltán Benyó; Éva Ruisanchez; Miriam Leszl-Ishiguro; Péter Sándor; Pál Pacher
Journal:  Am J Physiol Heart Circ Physiol       Date:  2016-01-29       Impact factor: 4.733

Review 4.  Endocannabinoids and the haematological system.

Authors:  M D Randall
Journal:  Br J Pharmacol       Date:  2007-08-20       Impact factor: 8.739

Review 5.  Monoacylglycerol lipase - a target for drug development?

Authors:  C J Fowler
Journal:  Br J Pharmacol       Date:  2012-07       Impact factor: 8.739

6.  Cannabinoids decrease the K(+) M-current in hippocampal CA1 neurons.

Authors:  P Schweitzer
Journal:  J Neurosci       Date:  2000-01-01       Impact factor: 6.167

7.  HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor.

Authors:  L Hanus; A Breuer; S Tchilibon; S Shiloah; D Goldenberg; M Horowitz; R G Pertwee; R A Ross; R Mechoulam; E Fride
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-07       Impact factor: 11.205

8.  Search for an endogenous cannabinoid-mediated effect in the sympathetic nervous system.

Authors:  Torsten Pfitzer; Nathalie Niederhoffer; Bela Szabo
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2005-01-20       Impact factor: 3.000

9.  A role for S1P and S1P1 in immature-B cell egress from mouse bone marrow.

Authors:  João Pedro Pereira; Ying Xu; Jason G Cyster
Journal:  PLoS One       Date:  2010-02-18       Impact factor: 3.240

10.  Noladin ether, a putative endocannabinoid, attenuates sensory neurotransmission in the rat isolated mesenteric arterial bed via a non-CB1/CB2 G(i/o) linked receptor.

Authors:  Marnie Duncan; Paul Millns; Darren Smart; James E Wright; David A Kendall; Vera Ralevic
Journal:  Br J Pharmacol       Date:  2004-05-17       Impact factor: 8.739
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