| Literature DB >> 9864247 |
M E Munk1, P Anding, A P Schettini, M G Cunha, S H Kaufmann.
Abstract
Serum levels of soluble tumor necrosis factor alpha receptor I (sTNF-RI) were elevated in patients with lepromatous (LL) reactional-state type II leprosy, and sTNF-RII levels were increased in patients with full tuberculoid (TT) or LL type II leprosy. The sTNF-R in sera from patients with type II leprosy, but not other forms of leprosy, inhibited recombinant TNF cytolytic activities in vitro. This suggests that sTNF-R regulatory activities are partially impaired in patients with leprosy.Entities:
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Year: 1999 PMID: 9864247 PMCID: PMC96328
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441