| Literature DB >> 9864244 |
J Vasi1, J Svensson, I M Frick, H P Müller.
Abstract
Protein MIG, from Streptococcus dysgalactiae, binds alpha2-macroglobulin and immunoglobulin G (IgG). MIG-derived fusion proteins with one to five IgG-binding repeats differed up to 72,000- fold in avidity for goat IgG, indicating a considerable cooperativity of the repeats. Significant sequence variation in the IgG-binding repeats was recognized. Protein MIG interacted with goat IgG1 via both the Fc and Fab parts.Entities:
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Year: 1999 PMID: 9864244 PMCID: PMC96325
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441