Literature DB >> 9861270

The Mectizan Donation Programme--a 10-year report.

H B Dull1, S E Meredith.   

Abstract

In the 10 years since 1987 when Merck & Co. announced a plan to donate its safe and effective microfilaricide, Mectizan (ivermectin, MSD), to treat onchocerciasis wherever and for as long as needed, more than 96 million treatments have been enabled in community-based treatment programmes in all 34 countries, in Africa, the Middle East, and Latin America, where the disease is endemic. It is expected that donations enabling some 33 million treatments will be approved in 1997. Since the beginning of the donation programme, it is estimated that some 19-20 million people have received at least one dose of the drug and that many have received their sixth, seventh, eighth, or even ninth annual dose.

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Year:  1998        PMID: 9861270

Source DB:  PubMed          Journal:  Ann Trop Med Parasitol        ISSN: 0003-4983


  5 in total

1.  Analysis of the mdr-1 gene in patients co-infected with Onchocerca volvulus and Loa loa who experienced a post-ivermectin serious adverse event.

Authors:  Catherine Bourguinat; Joseph Kamgno; Michel Boussinesq; Charles D Mackenzie; Roger K Prichard; Timothy G Geary
Journal:  Am J Trop Med Hyg       Date:  2010-07       Impact factor: 2.345

2.  Onchocerciasis transmission in Ghana: persistence under different control strategies and the role of the simuliid vectors.

Authors:  Poppy H L Lamberton; Robert A Cheke; Peter Winskill; Iñaki Tirados; Martin Walker; Mike Y Osei-Atweneboana; Nana-Kwadwo Biritwum; Anthony Tetteh-Kumah; Daniel A Boakye; Michael D Wilson; Rory J Post; María-Gloria Basañez
Journal:  PLoS Negl Trop Dis       Date:  2015-04-21

3.  Evaluation of the Diagnostic Performance of Onchocerca volvulus Linear Epitopes in a Peptide Enzyme-Linked Immunosorbent Assay.

Authors:  Ole Lagatie; Ann Verheyen; Erik Nijs; Bieke Van Dorst; Linda Batsa Debrah; Alex Debrah; Taniawati Supali; Erliyani Sartono; Lieven J Stuyver
Journal:  Am J Trop Med Hyg       Date:  2018-01-04       Impact factor: 2.345

Review 4.  Onchocerciasis control in Ghana (1974-2016).

Authors:  Nana-Kwadwo Biritwum; Dziedzom K de Souza; Odame Asiedu; Benjamin Marfo; Uche Veronica Amazigo; John Owusu Gyapong
Journal:  Parasit Vectors       Date:  2021-01-02       Impact factor: 3.876

5.  Relative neurotoxicity of ivermectin and moxidectin in Mdr1ab (-/-) mice and effects on mammalian GABA(A) channel activity.

Authors:  Cécile Ménez; Jean-François Sutra; Roger Prichard; Anne Lespine
Journal:  PLoS Negl Trop Dis       Date:  2012-11-01
  5 in total

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