Literature DB >> 9860936

New insights into the tumor suppression function of P27(kip1)

B E Clurman1, P Porter.   

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Year:  1998        PMID: 9860936      PMCID: PMC33928          DOI: 10.1073/pnas.95.26.15158

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


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  53 in total

1.  p27/Kip1 mutation found in breast cancer.

Authors:  K S Spirin; J F Simpson; S Takeuchi; N Kawamata; C W Miller; H P Koeffler
Journal:  Cancer Res       Date:  1996-05-15       Impact factor: 12.701

2.  Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle.

Authors:  S Coats; W M Flanagan; J Nourse; J M Roberts
Journal:  Science       Date:  1996-05-10       Impact factor: 47.728

Review 3.  Inhibitors of mammalian G1 cyclin-dependent kinases.

Authors:  C J Sherr; J M Roberts
Journal:  Genes Dev       Date:  1995-05-15       Impact factor: 11.361

4.  Translational control of p27Kip1 accumulation during the cell cycle.

Authors:  L Hengst; S I Reed
Journal:  Science       Date:  1996-03-29       Impact factor: 47.728

5.  A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer.

Authors:  T Kobayashi; Y Hirayama; E Kobayashi; Y Kubo; O Hino
Journal:  Nat Genet       Date:  1995-01       Impact factor: 38.330

6.  Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors.

Authors:  K Nakayama; N Ishida; M Shirane; A Inomata; T Inoue; N Shishido; I Horii; D Y Loh; K Nakayama
Journal:  Cell       Date:  1996-05-31       Impact factor: 41.582

7.  A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice.

Authors:  M L Fero; M Rivkin; M Tasch; P Porter; C E Carow; E Firpo; K Polyak; L H Tsai; V Broudy; R M Perlmutter; K Kaushansky; J M Roberts
Journal:  Cell       Date:  1996-05-31       Impact factor: 41.582

8.  Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

Authors:  H Kiyokawa; R D Kineman; K O Manova-Todorova; V C Soares; E S Hoffman; M Ono; D Khanam; A C Hayday; L A Frohman; A Koff
Journal:  Cell       Date:  1996-05-31       Impact factor: 41.582

9.  Inactivation of p27Kip1 by the viral E1A oncoprotein in TGFbeta-treated cells.

Authors:  A Mal; R Y Poon; P H Howe; H Toyoshima; T Hunter; M L Harter
Journal:  Nature       Date:  1996-03-21       Impact factor: 49.962

10.  Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27.

Authors:  M Pagano; S W Tam; A M Theodoras; P Beer-Romero; G Del Sal; V Chau; P R Yew; G F Draetta; M Rolfe
Journal:  Science       Date:  1995-08-04       Impact factor: 47.728

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  15 in total

1.  Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice.

Authors:  A E Lenferink; J F Simpson; L K Shawver; R J Coffey; J T Forbes; C L Arteaga
Journal:  Proc Natl Acad Sci U S A       Date:  2000-08-15       Impact factor: 11.205

2.  AKT1 induces caspase-mediated cleavage of the CDK inhibitor p27Kip1 during cell cycle progression in leukemia cells transformed by FLT3-ITD.

Authors:  Xinping Yang; Suiyang Liu; Surender Kharbanda; Richard M Stone
Journal:  Leuk Res       Date:  2011-12-03       Impact factor: 3.156

3.  Expression of p27(kip) and other cell cycle regulators in malignant peripheral nerve sheath tumors and neurofibromas: the emerging role of p27(kip) in malignant transformation of neurofibromas.

Authors:  H P Kourea; C Cordon-Cardo; M Dudas; D Leung; J M Woodruff
Journal:  Am J Pathol       Date:  1999-12       Impact factor: 4.307

4.  Control of cyclin-dependent kinase inhibitor p27 expression by cap-independent translation.

Authors:  W K Miskimins; G Wang; M Hawkinson; R Miskimins
Journal:  Mol Cell Biol       Date:  2001-08       Impact factor: 4.272

5.  Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions.

Authors:  Sandra S McAllister; Michelle Becker-Hapak; Giuseppe Pintucci; Michele Pagano; Steven F Dowdy
Journal:  Mol Cell Biol       Date:  2003-01       Impact factor: 4.272

6.  ErbB2/Neu-induced, cyclin D1-dependent transformation is accelerated in p27-haploinsufficient mammary epithelial cells but impaired in p27-null cells.

Authors:  Rebecca S Muraoka; Anne E G Lenferink; Brian Law; Elizabeth Hamilton; Dana M Brantley; L Renee Roebuck; Carlos L Arteaga
Journal:  Mol Cell Biol       Date:  2002-04       Impact factor: 4.272

7.  Cyclin dependent kinase inhibitor p27Kip1 expression in normal and neoplastic cervical epithelium.

Authors:  G Troncone; A Vetrani; G de Rosa; D Gerbasio; L Palombini
Journal:  J Clin Pathol       Date:  1999-12       Impact factor: 3.411

8.  A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination.

Authors:  V N Podust; J E Brownell; T B Gladysheva; R S Luo; C Wang; M B Coggins; J W Pierce; E S Lightcap; V Chau
Journal:  Proc Natl Acad Sci U S A       Date:  2000-04-25       Impact factor: 11.205

9.  Polypyrimidine tract-binding protein enhances the internal ribosomal entry site-dependent translation of p27Kip1 mRNA and modulates transition from G1 to S phase.

Authors:  Sungchan Cho; Jong Heon Kim; Sung Hoon Back; Sung Key Jang
Journal:  Mol Cell Biol       Date:  2005-02       Impact factor: 4.272

10.  Genetic variations in cell-cycle pathway and the risk of oral premalignant lesions.

Authors:  Yuanqing Ye; Scott M Lippman; J Jack Lee; Meng Chen; Marsha L Frazier; Margaret R Spitz; Xifeng Wu
Journal:  Cancer       Date:  2008-11-01       Impact factor: 6.860

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