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Literature DB >> 9859942

Feasibility study of lactate imaging of head and neck tumors.

E Adalsteinsson¹, D M Spielman, J M Pauly, D J Terris, G Sommer, A Macovski.

Abstract

A proton spectroscopic imaging sequence was used to investigate the feasibility of lactate imaging in head and neck tumors. The sequence employs a two-shot lactate editing method with inversion recovery for additional lipid suppression, and a restricted field of view to suppress motion artifacts. Variations in acquisition parameters and two different receive coils were investigated on twelve patients. Elevated lactate was detected in three patients, no lactate was observed in seven patients, and two studies were inconclusive because of severe motion or inhomogeneity artifacts. Best results were obtained with an anterior/posterior neck coil at a 288 ms echo time (TE).

Entities: Chemical Disease Species

Mesh：

Substances：
Lactic Acid

Year: 1998 PMID： 9859942 DOI： 10.1002/(sici)1099-1492(1998110)11:7<360::aid-nbm518>3.0.co;2-p

Source DB: PubMed Journal: NMR Biomed ISSN： 0952-3480 Impact factor: 4.044

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Cited

11 in total

1. Relationships between LDH-A, lactate, and metastases in 4T1 breast tumors.

Authors: Asif Rizwan; Inna Serganova; Raya Khanin; Hazem Karabeber; Xiaohui Ni; Sunitha Thakur; Kristen L Zakian; Ronald Blasberg; Jason A Koutcher
Journal: Clin Cancer Res Date: 2013-07-05 Impact factor: 12.531

2. In vivo 1H MR spectroscopy of human head and neck lymph node metastasis and comparison with oxygen tension measurements.

Authors: J M Star-Lack; E Adalsteinsson; M F Adam; D J Terris; H A Pinto; J M Brown; D M Spielman
Journal: AJNR Am J Neuroradiol Date: 2000-01 Impact factor: 3.825

3. Reliability of CT-based tumor volumetry after intraarterial chemotherapy in patients with small carcinoma of the oral cavity and the oropharynx.

Authors: Stefan Rohde; Adorján F Kovács; Joachim Berkefeld; Bernd Turowski
Journal: Neuroradiology Date: 2006-04-12 Impact factor: 2.804

Review 10. Current concepts and future of noninvasive procedures for diagnosing oral squamous cell carcinoma--a systematic review.

Authors: Esam Omar
Journal: Head Face Med Date: 2015-03-25 Impact factor: 2.151

Feasibility study of lactate imaging of head and neck tumors.

1. Relationships between LDH-A, lactate, and metastases in 4T1 breast tumors.

2. In vivo 1H MR spectroscopy of human head and neck lymph node metastasis and comparison with oxygen tension measurements.

3. Reliability of CT-based tumor volumetry after intraarterial chemotherapy in patients with small carcinoma of the oral cavity and the oropharynx.

4. In vivo proton MR spectroscopy of primary tumours, nodal and recurrent disease of the extracranial head and neck.

5. Lactate imaging with Hadamard-encoded slice-selective multiple quantum coherence chemical-shift imaging.

Review 6. Novel imaging approaches to head and neck cancer.

7. Early stage diagnosis of oral cancer using 1H NMR-based metabolomics.

8. J-difference lactate editing at 3.0 Tesla in the presence of strong lipids.

9. In vivo proton MR spectroscopy of primary and nodal nasopharyngeal carcinoma.

Review 10. Current concepts and future of noninvasive procedures for diagnosing oral squamous cell carcinoma--a systematic review.