Literature DB >> 9858985

[Survival of laboratory animals in argon-containing hypoxic gaseous environments].

P E Soldatov, A I D'iachenko, B N Pavlov, A P Fedotov, A P Chuguev.   

Abstract

Present paper is aimed at assessing the effect of hypoxic gaseous mixtures intended for the use as the fire suppression agents within closed volumes on the basis of argon with addition of carbonic acid on the body of mammalia. Three experiments were performed on the male white laboratory Wistar rats. It is indicated that argon adding to the hypoxic mixtures containing 4-5% volume increases animal survivability as compared to analogous nitrogen-based mixtures. An addition of 4-8% volume of carbonic acid impairs the of animal condition and reduces the survival rate. There noted a pronounced negative effect of the increased temperature on the survival time in the hypoxic media. One can draw inference about the principal possibility of using argon for formation of the hypoxic gaseous mixtures possessing fire suppression properties.

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Year:  1998        PMID: 9858985

Source DB:  PubMed          Journal:  Aviakosm Ekolog Med        ISSN: 0233-528X


  12 in total

1.  Argon Inhalation for 24 Hours After Onset of Permanent Focal Cerebral Ischemia in Rats Provides Neuroprotection and Improves Neurologic Outcome.

Authors:  Shuang Ma; Dongmei Chu; Litao Li; Jennifer A Creed; Yu-Mi Ryang; Huaxin Sheng; Wei Yang; David S Warner; Dennis A Turner; Ulrike Hoffmann
Journal:  Crit Care Med       Date:  2019-08       Impact factor: 7.598

2.  Delayed argon administration provides robust protection against cardiac arrest-induced neurological damage.

Authors:  Anne Brücken; Pinar Kurnaz; Christian Bleilevens; Matthias Derwall; Joachim Weis; Kay Nolte; Rolf Rossaint; Michael Fries
Journal:  Neurocrit Care       Date:  2015-02       Impact factor: 3.210

3.  Argon: a novel therapeutic option to treat neuronal ischemia and reperfusion injuries?

Authors:  Felix Ulbrich; Ulrich Goebel
Journal:  Neural Regen Res       Date:  2015-07       Impact factor: 5.135

Review 4.  Argon: systematic review on neuro- and organoprotective properties of an "inert" gas.

Authors:  Anke Höllig; Anita Schug; Astrid V Fahlenkamp; Rolf Rossaint; Mark Coburn
Journal:  Int J Mol Sci       Date:  2014-10-10       Impact factor: 5.923

5.  Argon inhalation attenuates retinal apoptosis after ischemia/reperfusion injury in a time- and dose-dependent manner in rats.

Authors:  Felix Ulbrich; Nils Schallner; Mark Coburn; Torsten Loop; Wolf Alexander Lagrèze; Julia Biermann; Ulrich Goebel
Journal:  PLoS One       Date:  2014-12-23       Impact factor: 3.240

Review 6.  The Molecular Pathway of Argon-Mediated Neuroprotection.

Authors:  Felix Ulbrich; Ulrich Goebel
Journal:  Int J Mol Sci       Date:  2016-10-31       Impact factor: 5.923

Review 7.  A complete review of preclinical and clinical uses of the noble gas argon: Evidence of safety and protection.

Authors:  Francesca Nespoli; Simone Redaelli; Laura Ruggeri; Francesca Fumagalli; Davide Olivari; Giuseppe Ristagno
Journal:  Ann Card Anaesth       Date:  2019 Apr-Jun

8.  Argon: neuroprotection in in vitro models of cerebral ischemia and traumatic brain injury.

Authors:  Philip D Loetscher; Jan Rossaint; Rolf Rossaint; Joachim Weis; Michael Fries; Astrid Fahlenkamp; Yu-Mi Ryang; Oliver Grottke; Mark Coburn
Journal:  Crit Care       Date:  2009-12-17       Impact factor: 9.097

9.  Bustling argon: biological effect.

Authors:  Zhouheng Ye; Rongjia Zhang; Xuejun Sun
Journal:  Med Gas Res       Date:  2013-10-03

10.  Argon Induces Protective Effects in Cardiomyocytes during the Second Window of Preconditioning.

Authors:  Britta Mayer; Josefin Soppert; Sandra Kraemer; Sabrina Schemmel; Christian Beckers; Christian Bleilevens; Rolf Rossaint; Mark Coburn; Andreas Goetzenich; Christian Stoppe
Journal:  Int J Mol Sci       Date:  2016-07-19       Impact factor: 5.923

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