| Literature DB >> 9858808 |
T Furukawa1, T Yatsuoka, E M Youssef, T Abe, T Yokoyama, S Fukushige, E Soeda, M Hoshi, Y Hayashi, M Sunamura, M Kobari, A Horii.
Abstract
DUSP6 (alias PYST1), one of the dual-specificity tyrosine phosphatases, is localized on 12q21, one of the regions of frequent allelic loss in pancreatic cancer. This gene is composed of three exons, and two forms of alternatively spliced transcripts are ubiquitously expressed. Although no mutations were observed in 26 pancreatic cancer cell lines, reduced expressions of the full-length transcripts were observed in some cell lines, which may suggest some role for DUSP6 in pancreatic carcinogenesis.Entities:
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Year: 1998 PMID： 9858808 DOI： 10.1159/000015091
Source DB: PubMed Journal: Cytogenet Cell Genet ISSN： 0301-0171