Literature DB >> 9858747

Sequence of a pyrimidine-selective Na+/nucleoside cotransporter from pig kidney, pkCNT1.

A M Pajor1.   

Abstract

A 3 kb cDNA called pkCNT1, a new member of the Na+/nucleoside cotransporter family, was cloned from pig kidney and sequenced. The sequence of pkCNT1 encodes a 647 amino acid protein that is 84% identical to the sequence of the rat pyrimidine-selective Na+/nucleoside cotransporter, rCNT1. pkCNT1 transports pyrimidines, such as thymidine and uridine, and has a Km for uridine of 9 microM.

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Year:  1998        PMID: 9858747     DOI: 10.1016/s0005-2736(98)00192-8

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  2 in total

1.  Molecular cloning of a Na+-dependent nucleoside transporter from rabbit intestine.

Authors:  K M Gerstin; M J Dresser; J Wang; K M Giacomini
Journal:  Pharm Res       Date:  2000-08       Impact factor: 4.200

2.  Genomic organization and functional characterization of the human concentrative nucleoside transporter-3 isoform (hCNT3) expressed in mammalian cells.

Authors:  Shuy-Vang Toan; Kenneth K W To; George P H Leung; Maria Olivia de Souza; Jeffrey L Ward; Chung-Ming Tse
Journal:  Pflugers Arch       Date:  2003-09-18       Impact factor: 3.657

  2 in total

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