| Literature DB >> 9858706 |
J M Philippe1, A Garces, O deLapeyière.
Abstract
The expression pattern of the fibroblast growth factor receptor Fgf-R1, R2 and R3 genes was studied in the chicken spinal cord using in situ hybridization (ISH). Unlike Fgf-R1 which is widely expressed in motoneurons, Fgf-R3 is expressed in a subset of motoneurons in the medial subdivision of the median motor column (MMCm) that also express Islet-1 and Lim-3. The motoneuron identity of the labelled cells was confirmed by double ISH and by single cell RT-PCR. Interestingly, E3.5 spinal cord motoneurons do not express Fgf-R3, suggesting the expression of Fgf-R3 in motoneurons begins with axonal growth. Copyright 1998 Elsevier Science Ireland Ltd. All Rights ReservedEntities:
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Year: 1998 PMID： 9858706 DOI： 10.1016/s0925-4773(98)00158-0
Source DB: PubMed Journal: Mech Dev ISSN： 0925-4773 Impact factor: 1.882