Literature DB >> 9858380

LTP in CA1 of the adult rat hippocampus and voltage-activated calcium channels.

Y Izumi1, C F Zorumski.   

Abstract

It is difficult to induce long-term potentiation (LTP) in CA1 of hippocampal slices from 120-day-old rats when a single 100 Hz, 1 s tetanus is administered in extracellular solution containing 2.0 mM calcium and 2.0 mM magnesium. However, in the presence of 2.5 mM calcium and 1.3 mM magnesium LTP is reliably induced by this same stimulus. Although the amplitude of LTP is similar to that observed in slices from 30-day-old rats, LTP in slices from mature rats is not inhibited by MK-801 but is blocked by nifedipine. These results suggest that factors contributing to LTP in slices from mature rats require careful consideration under different experimental paradigms.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9858380     DOI： 10.1097/00001756-199811160-00022

Source DB:  PubMed          Journal:  Neuroreport        ISSN： 0959-4965            Impact factor:   1.837


  6 in total

1.  L-type voltage-gated calcium channels are required for extinction, but not for acquisition or expression, of conditional fear in mice.

Authors:  Chris K Cain; Ashley M Blouin; Mark Barad
Journal:  J Neurosci       Date:  2002-10-15       Impact factor: 6.167

2.  Critical dependence of cAMP response element-binding protein phosphorylation on L-type calcium channels supports a selective response to EPSPs in preference to action potentials.

Authors:  P G Mermelstein; H Bito; K Deisseroth; R W Tsien
Journal:  J Neurosci       Date:  2000-01-01       Impact factor: 6.167

3.  A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat.

Authors:  Daniel A Clayton; Michael H Mesches; Enriquez Alvarez; Paula C Bickford; Michael D Browning
Journal:  J Neurosci       Date:  2002-05-01       Impact factor: 6.167

4.  Short-term environmental enrichment enhances synaptic plasticity in hippocampal slices from aged rats.

Authors:  Liana R Stein; Kazuko A O'Dell; Michiyo Funatsu; Charles F Zorumski; Yukitoshi Izumi
Journal:  Neuroscience       Date:  2016-05-18       Impact factor: 3.590

5.  Modulation of hippocampal long-term potentiation by slow increases in ethanol concentration.

Authors:  K Tokuda; C F Zorumski; Y Izumi
Journal:  Neuroscience       Date:  2007-03-07       Impact factor: 3.590

Review 6.  Role of Ca2+/Calmodulin-Dependent Protein Kinase Type II in Mediating Function and Dysfunction at Glutamatergic Synapses.

Authors:  Archana G Mohanan; Sowmya Gunasekaran; Reena Sarah Jacob; R V Omkumar
Journal:  Front Mol Neurosci       Date:  2022-06-20       Impact factor: 6.261
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.