Literature DB >> 985622

A model of spinal cord injury.

E Eidelberg, E Staten, J C Watkins, D McGraw, C McFadden.   

Abstract

We report here a model of submaximal spinal cord injury, employing direct thoracic cord compression in ferrets. This yields consistent and reproducible long term consequences on local cellular structure and on locomotive function. We show also that both the anatomical and functional losses can be measured objectively using simple techniques, and that useful long-tract mediated locomotion is preserved after severe axonal losses at the site of injury.

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Mesh:

Year:  1976        PMID: 985622

Source DB:  PubMed          Journal:  Surg Neurol        ISSN: 0090-3019


  2 in total

Review 1.  Translational spinal cord injury research: preclinical guidelines and challenges.

Authors:  Paul J Reier; Michael A Lane; Edward D Hall; Y D Teng; Dena R Howland
Journal:  Handb Clin Neurol       Date:  2012

Review 2.  Moving Forward: Recent Developments for the Ferret Biomedical Research Model.

Authors:  Randy A Albrecht; Wen-Chun Liu; Andrea J Sant; S Mark Tompkins; Andrew Pekosz; Victoria Meliopoulos; Sean Cherry; Paul G Thomas; Stacey Schultz-Cherry
Journal:  MBio       Date:  2018-07-17       Impact factor: 7.867

  2 in total

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