Literature DB >> 985569

The metabolism of the anti-tumour agent 5-(1-aziridinyl)-2,4-dinitrobenzamide (CB 1954).

M Jarman, D H Melzack, W C Ross.   

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Year:  1976        PMID： 985569     DOI： 10.1016/0006-2952(76)90451-2

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


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  5 in total

1.  Cyclophosphamides as hypoxia-activated diffusible cytotoxins: a theoretical study.

Authors:  J H Wu; C A Reynolds
Journal:  J Comput Aided Mol Des       Date:  2000-05       Impact factor: 3.686

2.  CB 1954 revisited. II. Toxicity and antitumour activity.

Authors:  P Workman; J E Morgan; K Talbot; K A Wright; J Donaldson; P R Twentyman
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333

3.  CB 1954 revisited. I. Disposition kinetics and metabolism.

Authors:  P Workman; R A White; K Talbot
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333

Review 4.  The bioactivation of CB 1954 and its use as a prodrug in antibody-directed enzyme prodrug therapy (ADEPT).

Authors:  R J Knox; F Friedlos; M P Boland
Journal:  Cancer Metastasis Rev       Date:  1993-06       Impact factor: 9.264

5.  2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPT.

Authors:  N A Helsby; D M Ferry; A V Patterson; S M Pullen; W R Wilson
Journal:  Br J Cancer       Date:  2004-03-08       Impact factor: 7.640
  5 in total

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