Literature DB >> 9855533

Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures.

W U Mirza1, I W Rak, V M Thadani, J J Cereghino, W R Garnett, L M Brown, Y Zhang, G W Belendiuk.   

Abstract

We evaluated the use of a new, controlled-release capsule form of carbamazepine, Carbatrol capsules, in an open-label, multicenter study of 124 patients with complex partial seizures. Ninety-one percent of the patients successfully completed the 6-month trial with good seizure control, with a significant improvement in quality of life. We conclude that switching patients with complex partial seizures from multiple daily-dose carbamazepine to twice-daily Carbatrol on a milligram-to-milligram basis is relatively safe.

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Year:  1998        PMID: 9855533     DOI: 10.1212/wnl.51.6.1727

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  6 in total

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Journal:  Clin Drug Investig       Date:  2005       Impact factor: 2.859

2.  Extended-release formulations of antiepileptic drugs: rationale and comparative value.

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Journal:  Epilepsy Curr       Date:  2009 Nov-Dec       Impact factor: 7.500

Review 3.  Extended-release formulations for the treatment of epilepsy.

Authors:  Meir Bialer
Journal:  CNS Drugs       Date:  2007       Impact factor: 5.749

4.  Extended-release carbamazepine capsules as monotherapy in bipolar disorder : pooled results from two randomised, double-blind, placebo-controlled trials.

Authors:  Richard H Weisler; Robert Hirschfeld; Andrew J Cutler; Thomas Gazda; Terence A Ketter; Paul E Keck; Alan Swann; Amir Kalali
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Review 5.  Immediate-release versus controlled-release carbamazepine in the treatment of epilepsy.

Authors:  Graham Powell; Matthew Saunders; Alexandra Rigby; Anthony G Marson
Journal:  Cochrane Database Syst Rev       Date:  2016-12-08

6.  Pharmacotherapeutics of epilepsy: use of lamotrigine and expectations for lamotrigine extended release.

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Journal:  Ther Clin Risk Manag       Date:  2008-10       Impact factor: 2.423

  6 in total

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