DNA short tandem repeat profiling of Chinese population in Taiwan determined by using an automated sequencer.

We performed a population study on a Taiwan population using a set of nine short tandem repeat (STR) loci and the amelogenin locus. Allele and genotype frequencies of the STR systems D3S1358, vWA, FGA, TH01, TPOX, CSF1PO, D5S818, D13S317 and D7S820 were determined by polymerase chain reaction followed by automated sequencer analysis. A total of 80 alleles could be observed, using all systems, in a population of 500 individuals. No new intermediate fragments were found in these systems. Allele frequencies showed no deviation from the Hardy-Weinberg equilibrium. The mean exclusion power (MEP) ranged from 0.294 for TPOX to 0.711 for FGA (the combined MEP was > 0.999), the discriminating power (DP) ranged from 0.782 for TPOX to 0.964 for FGA, (the combined DP was > 0.99999999949).