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Literature DB >> 985482

Binding of maytansine to rat brain tubulin.

F Mandelbaum-Shavit, M K Wolpert-DeFilippes, D G Johns.

Abstract

Entities: Chemical Species

Mesh：

Substances：

Year: 1976 PMID： 985482 DOI： 10.1016/0006-291x(76)90958-x

Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575

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16 in total

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3. A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs.

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Review 4. Antibody-DM1 conjugates as cancer therapeutics.

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Review 5. Antineoplastic drugs: clinical pharmacology and therapeutic use.

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6. Maytansinoid-antibody conjugates induce mitotic arrest by suppressing microtubule dynamic instability.

Authors: Emin Oroudjev; Manu Lopus; Leslie Wilson; Charlene Audette; Carmela Provenzano; Hans Erickson; Yelena Kovtun; Ravi Chari; Mary Ann Jordan
Journal: Mol Cancer Ther Date: 2010-10 Impact factor: 6.261

7. Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules.

Authors: Manu Lopus; Emin Oroudjev; Leslie Wilson; Sharon Wilhelm; Wayne Widdison; Ravi Chari; Mary Ann Jordan
Journal: Mol Cancer Ther Date: 2010-10 Impact factor: 6.261