Literature DB >> 9852768

Apoptosis of lymphocytes in mice administered lipopolysaccharide from Leptospira interrogans.

E Isogai1, H Isogai, T Kubota, N Fujii, S Hayashi, T Indoh, S Takagi, H Miura, K Kimura.   

Abstract

We report that administration of leptospiral lipopolysaccharide (LPS) in mice results in massive surface marker changes in the lymphocytes of the spleen. It appears that many of these changes relate to the large number of cells undergoing apoptosis. It is also shown that tumor necrosis factor-alpha (TNF-alpha) induces similar effects and is produced in large quantities after injection of leptospiral LPS. It is likely that cytokines such as TNF-alpha are involved in apoptosis.

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Year:  1998        PMID： 9852768     DOI： 10.1111/j.1439-0450.1998.tb00824.x

Source DB:  PubMed          Journal:  Zentralbl Veterinarmed B        ISSN： 0514-7166


  7 in total

Review 1.  Leptospirosis.

Authors:  P N Levett
Journal:  Clin Microbiol Rev       Date:  2001-04       Impact factor: 26.132

Review 2.  Leptospira: the dawn of the molecular genetics era for an emerging zoonotic pathogen.

Authors:  Albert I Ko; Cyrille Goarant; Mathieu Picardeau
Journal:  Nat Rev Microbiol       Date:  2009-10       Impact factor: 60.633

3.  The inhibition effect of antiserum on the motility of Leptospira.

Authors:  Yijie Guo; Shuichi Nakamura; Tasuke Ando; Hiroshi Yoneyama; Seishi Kudo; Emiko Isogai
Journal:  Curr Microbiol       Date:  2012-12-09       Impact factor: 2.188

4.  Cytotoxic activities of Leptospira interrogans hemolysin SphH as a pore-forming protein on mammalian cells.

Authors:  Seoung Hoon Lee; Sangduk Kim; Seung Chul Park; Min Ja Kim
Journal:  Infect Immun       Date:  2002-01       Impact factor: 3.441

5.  Interaction between Leptospiral Lipopolysaccharide and Toll-like Receptor 2 in Pig Fibroblast Cell Line, and Inhibitory Effect of Antibody against Leptospiral Lipopolysaccharide on Interaction.

Authors:  Yijie Guo; Tomokazu Fukuda; Shuichi Nakamura; Lanlan Bai; Jun Xu; Kengo Kuroda; Rintaro Tomioka; Hiroshi Yoneyama; Emiko Isogai
Journal:  Asian-Australas J Anim Sci       Date:  2015-02       Impact factor: 2.509

6.  Severe Leptospirosis Features in the Spleen Indicate Cellular Immunosuppression Similar to That Found in Septic Shock.

Authors:  Amaro Nunes Duarte-Neto; Julio Croda; Carla Pagliari; Francisco Garcia Soriano; Antonio Carlos Nicodemo; Maria Irma Seixas Duarte
Journal:  Front Immunol       Date:  2019-04-30       Impact factor: 7.561

7.  Complement pathway amplifies caspase-11-dependent cell death and endotoxin-induced sepsis severity.

Authors:  Brooke A Napier; Sky W Brubaker; Timothy E Sweeney; Patrick Monette; Greggory H Rothmeier; Nina A Gertsvolf; Andreas Puschnik; Jan E Carette; Purvesh Khatri; Denise M Monack
Journal:  J Exp Med       Date:  2016-10-03       Impact factor: 14.307
  7 in total

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