Literature DB >> 9852684

A highly polymorphic CA repeat marker at the human tumor necrosis factor alpha (TNFA alpha) locus.

K Tsukamoto1, N Ohta, Y Shirai, M Emi.   

Abstract

Tumor necrosis factor alpha (TNF alpha) in activated monocytes exerts cytotoxic activity and has a variety of other biological effects. We isolated a polymorphic dinucleotide (CA) repeat sequence from a genomic clone containing the gene located at 6p21.3. High heterozygosity (0.80) makes this polymorphism a useful marker in the genetic study of disorders affecting immunological response and cell differentiation.

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Year:  1998        PMID： 9852684     DOI： 10.1007/s100380050090

Source DB:  PubMed          Journal:  J Hum Genet        ISSN： 1434-5161            Impact factor:   3.172


  6 in total

1.  Proinflammatory cytokine gene polymorphisms among Hashimoto's thyroiditis patients.

Authors:  Rong-Hsing Chen; Chwen-Tzuei Chang; Wei-Chi Chen; Chang-Hai Tsai; Fuu-Jen Tsai
Journal:  J Clin Lab Anal       Date:  2006       Impact factor: 2.352

2.  Association of tumor necrosis factor a-2 and a-8 microsatellite alleles with human papillomavirus and squamous intraepithelial lesions among women in Brazil.

Authors:  R T Simões; M A G Gonçalves; E A Donadi; A L Simões; J S R Bettini; G Duarte; S M Quintana; M W P Carvalho; E G Soares
Journal:  J Clin Microbiol       Date:  2005-08       Impact factor: 5.948

3.  TNF microsatellite alleles in Brazilian Chagasic patients.

Authors:  Viriato Campelo; Roberto O Dantas; Renata T Simões; Celso T Mendes-Junior; Sandra M B Sousa; Aguinaldo L Simões; Eduardo A Donadi
Journal:  Dig Dis Sci       Date:  2007-08-23       Impact factor: 3.199

4.  The influence of tumor necrosis factor microsatellite polymorphisms on patient survival following hematopoietic stem cell transplantation.

Authors:  Katarina Stingl; Renata Zunec; Ranka Serventi-Seiwerth; Boris Labar; Zorana Grubić
Journal:  Croat Med J       Date:  2012-02-15       Impact factor: 1.351

5.  Lack of association between TNF-α gene polymorphisms at position -308 A, -850T and risk of simple febrile convulsion in pediatric patients.

Authors:  Abolfazl Khoshdel; Soleman Kheiri; Roya Habibian; Ahora Nozari; Azar Baradaran
Journal:  Adv Biomed Res       Date:  2012-12-28

Review 6.  TNF-α gene polymorphisms and expression.

Authors:  Radwa R El-Tahan; Ahmed M Ghoneim; Noha El-Mashad
Journal:  Springerplus       Date:  2016-09-07
  6 in total

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