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Literature DB >> 984858

Photochemotherapy of vitiligo. Use of orally administered psoralens and a high-intensity long-wave ultraviolet light system.

J A Parrish, T B Fitzpatrick, C Shea, M A Pathak.

Abstract

A new light source that provides high-intensity ultraviolet light (UVA) (300 to 400 nm) to the entire body surface makes orally administered psoralen treatment of vitilligo with an artificial light practical. In the 26 patients studied, the degree of repigmentation with either trioxsalen (TMP) or methoxsalen (8-MOP) and high intensity UVA was at least as great as that with the same oral agents and sunlight. With artificial UVA and similar treatment conditions, the two psoralen derivatives were compared in the treatment of vitiligo; TMP stimulated repigmentation as well as 8-MOP and caused fewer side effects.

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Year: 1976 PMID： 984858 DOI： 10.1001/archderm.112.11.1531

Source DB: PubMed Journal: Arch Dermatol ISSN： 0003-987X

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Cited

13 in total

Review 1. Determination of 8-methoxypsoralen in serum, aqueous, and lens: relation to long-wave ultraviolet phototoxicity in experimental and clinical photochemotherapy.

Authors: W B Glew
Journal: Trans Am Ophthalmol Soc Date: 1979

2. Impairement of thymus derived rosette forming cells during photochemotherapy (psoralen--U.V.A.).

Authors: J P Ortonne; A Claudy; A Alario; J Thivolet
Journal: Arch Dermatol Res Date: 1978-07-28 Impact factor: 3.017

Review 3. Guidelines for the treatment of vitiligo.

Authors: C Antoniou; A Katsambas
Journal: Drugs Date: 1992-04 Impact factor: 9.546

4. Incidence of nonmelanoma skin cancer in a cohort of patients with vitiligo.

Authors: Camile L Hexsel; Melody J Eide; Christine C Johnson; Richard Krajenta; Gordon Jacobsen; Iltefat Hamzavi; Henry W Lim
Journal: J Am Acad Dermatol Date: 2009-04-17 Impact factor: 11.527

5. Mechanism of action of psoralens: isobologram analysis reveals that ultraviolet light potentiation of psoralen action is not additive but synergistic.

Authors: E J Yurkow; J D Laskin
Journal: Cancer Chemother Pharmacol Date: 1991 Impact factor: 3.333

Photochemotherapy of vitiligo. Use of orally administered psoralens and a high-intensity long-wave ultraviolet light system.

Review 1. Determination of 8-methoxypsoralen in serum, aqueous, and lens: relation to long-wave ultraviolet phototoxicity in experimental and clinical photochemotherapy.

2. Impairement of thymus derived rosette forming cells during photochemotherapy (psoralen--U.V.A.).

Review 3. Guidelines for the treatment of vitiligo.

4. Incidence of nonmelanoma skin cancer in a cohort of patients with vitiligo.

5. Mechanism of action of psoralens: isobologram analysis reveals that ultraviolet light potentiation of psoralen action is not additive but synergistic.

6. Single-hair follicular unit transplant for stable vitiligo.

Review 7. Photochemotherapy in psoriasis: a review.

8. Evolution and evaluation of autologous mini punch grafting in vitiligo.

9. Immunohistochemical detection of P53 and Mdm2 in vitiligo.

10. Evaluation of PUVA-Induced Skin Side Effects in Patients Referred to the Imam Reza Hospital of Mashhad in 2005-2007.