Literature DB >> 984770

Pharmacokinetic interpretation of cephradine levels in serum after intravenous and extravascular administration in humans.

E S Rattie, P D Bernardo, J J Ravin.   

Abstract

Pharmacokinetic parameters were calculated from intravenous data based upon a two-compartment open model. These parameters were subsequently used to determine the absorption rates and bioavailability of cephradine administered intramuscularly and orally. The results indicate that cephradine obeys dose-independent kinetics and that biological availability is complete from all dosage forms.

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Year:  1976        PMID： 984770      PMCID： PMC429736          DOI： 10.1128/AAC.10.2.283

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

Review 1.  Cephradine--a summary of preclinical studies and clinical pharmacology.

Authors:  E S Neiss
Journal:  J Ir Med Assoc       Date:  1973-03-24

2.  Cephradine. Antibacterial activity and clinical effectiveness.

Authors:  J Klastersky; D Daneau; D Weerts
Journal:  Chemotherapy       Date:  1973       Impact factor: 2.544

3.  Shortcomings in pharmacokinetic analysis by conceiving the body to exhibit properties of a single compartment.

Authors:  S Riegelman; J C Loo; M Rowland
Journal:  J Pharm Sci       Date:  1968-01       Impact factor: 3.534

4.  Cephradine in the treatment of intestinal infections caused by Shigella or Salmonella organisms.

Authors:  L Landa
Journal:  Curr Ther Res Clin Exp       Date:  1972-08

5.  Cephradine absorption and excretion in fasting and nonfasting volunteers.

Authors:  C Harvengt; P De Schepper; F Lamy; J Hansen
Journal:  J Clin Pharmacol New Drugs       Date:  1973-01

6.  Cephradine: absorption, excretion, and tissue distribution in animals of a new cephalosporin antibiotic.

Authors:  I Weliky; H H Gadebusch; K Kripalani; P Arnow; E C Schreiber
Journal:  Antimicrob Agents Chemother       Date:  1974-01       Impact factor: 5.191

7.  Comparison of the chemotherapeutic and pharmacodynamic activities of cephradine, cephalothin, and cephaloridine in mice.

Authors:  G J Miraglia; K J Renz; H H Gadebusch
Journal:  Antimicrob Agents Chemother       Date:  1973-02       Impact factor: 5.191
  7 in total
  2 in total

Review 1.  Interethnic differences in pharmacokinetics of antibacterials.

Authors:  Danny Tsai; Janattul-Ain Jamal; Joshua S Davis; Jeffrey Lipman; Jason A Roberts
Journal:  Clin Pharmacokinet       Date:  2015-03       Impact factor: 6.447

2.  Physiologically Based Pharmacokinetic Modeling of Renally Cleared Drugs in Pregnant Women.

Authors:  André Dallmann; Ibrahim Ince; Juri Solodenko; Michaela Meyer; Stefan Willmann; Thomas Eissing; Georg Hempel
Journal:  Clin Pharmacokinet       Date:  2017-12       Impact factor: 6.447
  2 in total

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