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Literature DB >> 984759

Gentamicin- and cephalothin-associated rises in blood urea nitrogen.

Abstract

Standardized rates of drug-attributed rises in blood urea nitrogen were 8.6%, 2.9%, and 9.3%, respectively, in patients receiving gentamicin alone, cephalothin alone, and both drugs together. These results provide evidence against a substantial synergism between the two drugs in the production of impaired renal function.

Entities: Chemical Disease Species

Mesh：

Substances：
Gentamicins
Cephalothin

Year: 1976 PMID： 984759 PMCID： PMC429692 DOI： 10.1128/AAC.10.1.80

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

12 in total

1. Nephrotoxicity of combined cephalothin-gentamicin regimen.

Authors: F Cabanillas; R C Burgos; C Rodríguez; C Baldizón
Journal: Arch Intern Med Date: 1975-06

2. Nephrotoxicity associated with cephalothin administration.

Authors: P C Carling; B A Idelson; A A Casano; E A Alexander; W R McCabe
Journal: Arch Intern Med Date: 1975-06

3. Acute renal failure during cephalothin therapy.

Authors: J R Burton; N S Lichtenstein; R B Colvin; N E Hyslop
Journal: JAMA Date: 1974-08-05 Impact factor: 56.272

4. [Nephrotoxicity of cephalotin-gentamycin association. Clinical study of 4 cases].

Authors: A Masbernard; J Lainée; A Laurens; A Portal; C Giudicelli; Ch Lombard; F D'Audibert; C D Bourguet
Journal: Ann Med Interne (Paris) Date: 1974-10

5. Nephrotoxicity of aminoglycosides and gentamicin.

Authors: F G Falco; H M Smith; G M Arcieri
Journal: J Infect Dis Date: 1969 Apr-May Impact factor: 5.226

6. Anuria and acute tubular necrosis associated with gentamicin and cephalothin.

Authors: S N Bobrow; E Jaffe; R C Young
Journal: JAMA Date: 1972-12-18 Impact factor: 56.272

7. Declining renal function associated with administration of cephalothin.

Authors: M J Pickering; G R Spooner; A de Quesada; J R Cade
Journal: South Med J Date: 1970-04 Impact factor: 0.954

8. Acute renal failure associated with combined gentamicin and cephalothin therapy.

Authors: J P Fillastre; R Laumonier; G Humbert; D Dubois; J Metayer; A Delpech; J Leroy; M Robert
Journal: Br Med J Date: 1973-05-19

9. Immunization with live types 7 and 4 adenovirus vaccines. I. Safety, infectivity, antigenicity, and potency of adenovirus type 7 vaccine in humans.

Authors: F H Top; R A Grossman; P J Bartelloni; H E Segal; B A Dudding; P K Russell; E L Buescher
Journal: J Infect Dis Date: 1971-08 Impact factor: 5.226

10. Relative nephrotoxicity of cephalosporin antibiotics in an animal model.

Authors: A L Linton; R R Bailey; D I Turnbull
Journal: Can Med Assoc J Date: 1972-09-09 Impact factor: 8.262

8 in total

Review 1. Drug interactions that matter. A critical reappraisal.

Authors: G T McInnes; M J Brodie
Journal: Drugs Date: 1988-07 Impact factor: 9.546

Review 2. Side effects of cephalosporins.

Authors: S R Norrby
Journal: Drugs Date: 1987 Impact factor: 9.546

Gentamicin- and cephalothin-associated rises in blood urea nitrogen.

1. Nephrotoxicity of combined cephalothin-gentamicin regimen.

2. Nephrotoxicity associated with cephalothin administration.

3. Acute renal failure during cephalothin therapy.

4. [Nephrotoxicity of cephalotin-gentamycin association. Clinical study of 4 cases].

5. Nephrotoxicity of aminoglycosides and gentamicin.

6. Anuria and acute tubular necrosis associated with gentamicin and cephalothin.

7. Declining renal function associated with administration of cephalothin.

8. Acute renal failure associated with combined gentamicin and cephalothin therapy.

9. Immunization with live types 7 and 4 adenovirus vaccines. I. Safety, infectivity, antigenicity, and potency of adenovirus type 7 vaccine in humans.

10. Relative nephrotoxicity of cephalosporin antibiotics in an animal model.

Review 1. Drug interactions that matter. A critical reappraisal.

Review 2. Side effects of cephalosporins.

3. Effect of cefamandole nafate on the toxicity of tobramycin.

4. Tobramycin nephrotoxicity: failure of cefotaxime to potentiate renal toxicity.

5. Evaluation of three antibiotic programs in newborn infants.

6. Pharmacology and efficacy of netilmicin.

7. Amikacin and cephalothin: empiric regimen for granulocytopenic cancer patients.

Review 8. [Tobramycin concentrations in human renal tissue (author's transl)].