Literature DB >> 9847340

Dynamics of human immunodeficiency virus type 1 replication in vertically infected infants.

K Luzuriaga1, H Wu, M McManus, P Britto, W Borkowsky, S Burchett, B Smith, L Mofenson, J L Sullivan.   

Abstract

Plasma human immunodeficiency virus type 1 (HIV-1) turnover and kinetics were studied in children aged 15 days to 2 years following the initiation of a triple antiretroviral drug regimen consisting of zidovudine, lamivudine, and nevirapine. HIV-1 turnover was at least as rapid as that previously described in adults; turnover rates were more rapid in infants and children aged 3 months to 2 years than in infants less than 3 months of age. These data confirm the central role of HIV-1 replication in the pathogenesis of vertical HIV-1 infection and reinforce the importance of early, potent combination therapies for the long-term control of HIV-1 replication.

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Year:  1999        PMID： 9847340      PMCID： PMC103841     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  29 in total

Review 1.  HIV viral load markers in clinical practice.

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Journal:  Nat Med       Date:  1996-06       Impact factor: 53.440

2.  In vivo compartmentalization of human immunodeficiency virus: evidence from the examination of pol sequences from autopsy tissues.

Authors:  J K Wong; C C Ignacio; F Torriani; D Havlir; N J Fitch; D D Richman
Journal:  J Virol       Date:  1997-03       Impact factor: 5.103

3.  Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus.

Authors:  P Borrow; H Lewicki; X Wei; M S Horwitz; N Peffer; H Meyers; J A Nelson; J E Gairin; B H Hahn; M B Oldstone; G M Shaw
Journal:  Nat Med       Date:  1997-02       Impact factor: 53.440

4.  HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time.

Authors:  A S Perelson; A U Neumann; M Markowitz; J M Leonard; D D Ho
Journal:  Science       Date:  1996-03-15       Impact factor: 47.728

5.  HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy.

Authors:  J M Coffin
Journal:  Science       Date:  1995-01-27       Impact factor: 47.728

6.  Age- and time-related changes in extracellular viral load in children vertically infected by human immunodeficiency virus.

Authors:  K McIntosh; A Shevitz; D Zaknun; J Kornegay; P Chatis; N Karthas; S K Burchett
Journal:  Pediatr Infect Dis J       Date:  1996-12       Impact factor: 2.129

7.  Viral measurement by polymerase chain reaction-based assays in human immunodeficiency virus-infected infants.

Authors:  P E Palumbo; S Kwok; S Waters; Y Wesley; D Lewis; N McKinney; A Bardeguez; E M Connor; J M Oleske
Journal:  J Pediatr       Date:  1995-04       Impact factor: 4.406

8.  Reduction of HIV concentration during acute infection: independence from a specific immune response.

Authors:  A N Phillips
Journal:  Science       Date:  1996-01-26       Impact factor: 47.728

9.  Prognosis in HIV-1 infection predicted by the quantity of virus in plasma.

Authors:  J W Mellors; C R Rinaldo; P Gupta; R M White; J A Todd; L A Kingsley
Journal:  Science       Date:  1996-05-24       Impact factor: 47.728

10.  Early HIV-1 envelope-specific cytotoxic T lymphocyte responses in vertically infected infants.

Authors:  C A Pikora; J L Sullivan; D Panicali; K Luzuriaga
Journal:  J Exp Med       Date:  1997-04-07       Impact factor: 14.307
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  21 in total

1.  A stable latent reservoir for HIV-1 in resting CD4(+) T lymphocytes in infected children.

Authors:  D Persaud; T Pierson; C Ruff; D Finzi; K R Chadwick; J B Margolick; A Ruff; N Hutton; S Ray; R F Siliciano
Journal:  J Clin Invest       Date:  2000-04       Impact factor: 14.808

Review 2.  Nevirapine: a review of its use in the prevention and treatment of paediatric HIV infection.

Authors:  A Bardsley-Elliot; C M Perry
Journal:  Paediatr Drugs       Date:  2000 Sep-Oct       Impact factor: 3.022

3.  Nevirapine: an option for preventing as well as treating paediatric HIV infection.

Authors: 
Journal:  Afr Health Sci       Date:  2001-08       Impact factor: 0.927

4.  HIV type 1 (HIV-1) proviral reservoirs decay continuously under sustained virologic control in HIV-1-infected children who received early treatment.

Authors:  Katherine Luzuriaga; Barbara Tabak; Manuel Garber; Ya Hui Chen; Carrie Ziemniak; Margaret M McManus; Danielle Murray; Matthew C Strain; Douglas D Richman; Tae-Wook Chun; Coleen K Cunningham; Deborah Persaud
Journal:  J Infect Dis       Date:  2014-05-21       Impact factor: 5.226

5.  In-utero infection with HIV-1 associated with suppressed lymphoproliferative responses at birth.

Authors:  B Lohman-Payne; T Sandifer; M OhAinle; C Crudder; J Lynch; M M Omenda; J Maroa; K Fowke; G C John-Stewart; C Farquhar
Journal:  Clin Exp Immunol       Date:  2014-10       Impact factor: 4.330

6.  Nevirapine Resistance in Previously Nevirapine-Unexposed HIV-1-Infected Kenyan Infants Initiating Early Antiretroviral Therapy.

Authors:  Bhavna H Chohan; Kenneth Tapia; Sarah Benki-Nugent; Brian Khasimwa; Musa Ngayo; Elizabeth Maleche-Obimbo; Dalton Wamalwa; Julie Overbaugh; Grace John-Stewart
Journal:  AIDS Res Hum Retroviruses       Date:  2015-04-22       Impact factor: 2.205

Review 7.  The role of non-nucleoside reverse transcriptase inhibitors in children with HIV-1 infection.

Authors:  S Maddocks; D Dwyer
Journal:  Paediatr Drugs       Date:  2001       Impact factor: 3.022

8.  Immune reconstitution in human immunodeficiency virus type 1-infected children with different virological responses to anti-retroviral therapy.

Authors:  A Anselmi; D Vendrame; O Rampon; C Giaquinto; M Zanchetta; A De Rossi
Journal:  Clin Exp Immunol       Date:  2007-10-22       Impact factor: 4.330

9.  Suppression of human immunodeficiency virus type 1 viral load during acute measles.

Authors:  William J Moss; Susana Scott; Zaza Ndhlovu; Mwaka Monze; Felicity T Cutts; Thomas C Quinn; Diane E Griffin
Journal:  Pediatr Infect Dis J       Date:  2009-01       Impact factor: 2.129

10.  Rapid human immunodeficiency virus decay in highly active antiretroviral therapy (HAART)-experienced children after starting mega-HAART.

Authors:  Nottasorn Plipat; Ping K Ruan; Terence Fenton; Ram Yogev
Journal:  J Virol       Date:  2004-10       Impact factor: 5.103
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