Literature DB >> 9846630

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors.

D Colquhoun1.   

Abstract

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Year:  1998        PMID: 9846630      PMCID: PMC1565672          DOI: 10.1038/sj.bjp.0702164

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


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  325 in total

1.  Allosteric control of gating and kinetics at P2X(4) receptor channels.

Authors:  B S Khakh; W R Proctor; T V Dunwiddie; C Labarca; H A Lester
Journal:  J Neurosci       Date:  1999-09-01       Impact factor: 6.167

2.  Vertical shifts in self-administration dose-response functions predict a drug-vulnerable phenotype predisposed to addiction.

Authors:  P V Piazza; V Deroche-Gamonent; F Rouge-Pont; M Le Moal
Journal:  J Neurosci       Date:  2000-06-01       Impact factor: 6.167

3.  Allosteric modulators affect the efficacy of partial agonists for recombinant GABA(A) receptors.

Authors:  G Maksay; S A Thompson; K A Wafford
Journal:  Br J Pharmacol       Date:  2000-04       Impact factor: 8.739

4.  Agonist binding to G-protein coupled receptors.

Authors:  P G Strange
Journal:  Br J Pharmacol       Date:  2000-02       Impact factor: 8.739

5.  Substrate turnover by transporters curtails synaptic glutamate transients.

Authors:  S Mennerick; W Shen; W Xu; A Benz; K Tanaka; K Shimamoto; K E Isenberg; J E Krause; C F Zorumski
Journal:  J Neurosci       Date:  1999-11-01       Impact factor: 6.167

6.  Single-channel properties of neuronal GABAA receptors from mice lacking the 2 subunit.

Authors:  M Lorez; D Benke; B Luscher; H Mohler; J A Benson
Journal:  J Physiol       Date:  2000-08-15       Impact factor: 5.182

7.  Disparate ligand-mediated Ca(2+) responses by wild-type, mutant Ser(200)Ala and Ser(204)Ala alpha(2A)-adrenoceptor: G(alpha15) fusion proteins: evidence for multiple ligand-activation binding sites.

Authors:  P J Pauwels; F C Colpaert
Journal:  Br J Pharmacol       Date:  2000-08       Impact factor: 8.739

8.  Agonist Trapping by GABAA Receptor Channels.

Authors:  M T Bianchi; R L Macdonald
Journal:  J Neurosci       Date:  2001-12-01       Impact factor: 6.167

9.  Subunit interactions and AMPA receptor desensitization.

Authors:  A Robert; S N Irizarry; T E Hughes; J R Howe
Journal:  J Neurosci       Date:  2001-08-01       Impact factor: 6.167

10.  On the activation of soluble guanylyl cyclase by nitric oxide.

Authors:  Tomas C Bellamy; John Wood; John Garthwaite
Journal:  Proc Natl Acad Sci U S A       Date:  2001-12-18       Impact factor: 11.205

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