| Literature DB >> 9846124 |
Abstract
Product inhibition has provided the limiting barrier to efficient template-directed ligation and polymerization reactions. Here we review the attempts to circumvent this limitation and outline a translation strategy that does overcome the barrier and allows the information encoded in DNA to be read and amplified into backbone-modified oligonucleotides.Mesh：
Substances：
Year: 1998 PMID： 9846124 DOI： 10.1002/(SICI)1097-0282(1998)48:1<19::AID-BIP3>3.0.CO;2-I
Source DB: PubMed Journal: Biopolymers ISSN： 0006-3525 Impact factor: 2.505