| Literature DB >> 9844819 |
F Guilhot1, L Lacotte-Thierry.
Abstract
Interferon-alpha has been shown to induce complete haematologic responses in chronic myelogenous leukemia patients and also cytogenetic responses. There is a clear correlation between cytogenetic responses and survival improvement. There is not a unique mechanism of action of IFN-alpha. IFN-alpha acts directly against leukemic cells and there are also other mechanisms of action such as immune stimulation, gene regulation and growth factors or interleukin stimulation.Entities:
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Year: 1998 PMID： 9844819
Source DB: PubMed Journal: Hematol Cell Ther ISSN： 1269-3286