Literature DB >> 9843934

Compression, gain, and nonlinear distortion in an active cochlear model with subpartitions.

R S Chadwick1.   

Abstract

The propagation of inhomogeneous, weakly nonlinear waves is considered in a cochlear model having two degrees of freedom that represent the transverse motions of the tectorial and basilar membranes within the organ of Corti. It is assumed that nonlinearity arises from the saturation of outer hair cell active force generation. I use multiple scale asymptotics and treat nonlinearity as a correction to a linear hydroelastic wave. The resulting theory is used to explain experimentally observed features of the response of the cochlear partition to a pure tone, including: the amplification of the response in a healthy cochlea vs a dead one; the less than linear growth rate of the response to increasing sound pressure level; and the amount of distortion to be expected at high and low frequencies at basal and apical locations, respectively. I also show that the outer hair cell nonlinearity generates retrograde waves.

Mesh:

Year:  1998        PMID: 9843934      PMCID: PMC24494          DOI: 10.1073/pnas.95.25.14594

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  16 in total

1.  Dependence of cellular responses on signal level.

Authors:  S M Khanna; M Ulfendahl; A Flock
Journal:  Acta Otolaryngol Suppl       Date:  1989

2.  The origin of periodicity in the spectrum of evoked otoacoustic emissions.

Authors:  G Zweig; C A Shera
Journal:  J Acoust Soc Am       Date:  1995-10       Impact factor: 1.840

3.  Active control of waves in a cochlear model with subpartitions.

Authors:  R S Chadwick; E K Dimitriadis; K H Iwasa
Journal:  Proc Natl Acad Sci U S A       Date:  1996-03-19       Impact factor: 11.205

4.  Biophysics of the cochlea. II: Stationary nonlinear phenomenology.

Authors:  R Nobili; F Mammano
Journal:  J Acoust Soc Am       Date:  1996-04       Impact factor: 1.840

5.  Resonant tectorial membrane motion in the inner ear: its crucial role in frequency tuning.

Authors:  A W Gummer; W Hemmert; H P Zenner
Journal:  Proc Natl Acad Sci U S A       Date:  1996-08-06       Impact factor: 11.205

6.  A temporal bone preparation for the study of cochlear micromechanics at the cellular level.

Authors:  M Ulfendahl; A Flock; S M Khanna
Journal:  Hear Res       Date:  1989-06-15       Impact factor: 3.208

7.  Nonlinear mechanics at the apex of the guinea-pig cochlea.

Authors:  N P Cooper; W S Rhode
Journal:  Hear Res       Date:  1995-02       Impact factor: 3.208

8.  The effect of efferent stimulation on basilar membrane displacement in the basal turn of the guinea pig cochlea.

Authors:  E Murugasu; I J Russell
Journal:  J Neurosci       Date:  1996-01       Impact factor: 6.167

9.  Self-suppression in a locally active nonlinear model of the cochlea: a quasilinear approach.

Authors:  L J Kanis; E de Boer
Journal:  J Acoust Soc Am       Date:  1993-12       Impact factor: 1.840

10.  Furosemide alters organ of corti mechanics: evidence for feedback of outer hair cells upon the basilar membrane.

Authors:  M A Ruggero; N C Rich
Journal:  J Neurosci       Date:  1991-04       Impact factor: 6.167

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  5 in total

1.  Response to a pure tone in a nonlinear mechanical-electrical-acoustical model of the cochlea.

Authors:  Julien Meaud; Karl Grosh
Journal:  Biophys J       Date:  2012-03-20       Impact factor: 4.033

2.  Dual traveling waves in an inner ear model with two degrees of freedom.

Authors:  Jessica S Lamb; Richard S Chadwick
Journal:  Phys Rev Lett       Date:  2011-08-16       Impact factor: 9.161

Review 3.  Modelling cochlear mechanics.

Authors:  Guangjian Ni; Stephen J Elliott; Mohammad Ayat; Paul D Teal
Journal:  Biomed Res Int       Date:  2014-07-23       Impact factor: 3.411

Review 4.  Analytical and numerical modeling of the hearing system: Advances towards the assessment of hearing damage.

Authors:  Annalisa De Paolis; Marom Bikson; Jeremy T Nelson; J Alexander de Ru; Mark Packer; Luis Cardoso
Journal:  Hear Res       Date:  2017-02-02       Impact factor: 3.208

5.  Phase of shear vibrations within cochlear partition leads to activation of the cochlear amplifier.

Authors:  Jessica S Lamb; Richard S Chadwick
Journal:  PLoS One       Date:  2014-02-14       Impact factor: 3.240

  5 in total

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