Literature DB >> 9842787

Association of recurrent suicidal ideation with nonremission from acute mixed mania.

J F Goldberg1, J L Garno, A C Leon, J H Kocsis, L Portera.   

Abstract

OBJECTIVE: The authors' goal was to examine suicidality in relation to acute symptom remission in inpatients with mixed and pure bipolar disorder.
METHOD: Using chart review of 184 adult inpatients with bipolar I disorder, the authors assessed patients' past and current suicidality, other psychopathology, treatment, and remission.
RESULTS: Past, current, and recurrent suicidality were significantly more common among patients with mixed mania than among those with pure mania. The probability of remission declined by 49% for every suicide attempt made before the index manic episode. Mixed mania, multiple previous hospitalizations, and previous suicide attempts were significantly associated with current suicidality.
CONCLUSIONS: Suicidality is linked with mixed manic states and may be a clinical marker for recurrent dysphoric mania. Multiple suicide attempts are associated with nonremission from mixed manic episodes.

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Year:  1998        PMID: 9842787     DOI: 10.1176/ajp.155.12.1753

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


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Review 10.  Epidemiology, diagnosis and management of mixed mania.

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