Literature DB >> 9842046

Severe hypophosphatemia in children with kwashiorkor is associated with increased mortality.

M J Manary1, C A Hart, M P Whyte.   

Abstract

Severe hypophosphatemia, serum phosphate concentration <0.32 mmol/L (<1.0 mg/dL), occurred in 8 of 68 (12%) of children with kwashiorkor within 48 hours of admission; 5 of 8 (63%) of these children died, compared with 13 of 60 (22%) children without severe hypophosphatemia (P <.02). Dermatosis and dehydration were significantly correlated with severe hypophosphatemia, but these clinical signs could not reliably predict fatal cases. Severe hypophosphatemia seems to be common and life-threatening in children with kwashiorkor in Malawi.

Entities:  

Keywords:  Africa; Africa South Of The Sahara; Age Factors; Biology; Child; Deficiency Diseases; Demographic Factors; Developing Countries; Diseases; Eastern Africa; English Speaking Africa; Excess Mortality; Hemic System; Kwashiorkor; Malawi; Mortality; Nutrition Disorders; Physiology; Population; Population Characteristics; Population Dynamics; Research Report; Serum Phosphorus Level; Youth

Mesh:

Year:  1998        PMID: 9842046     DOI: 10.1016/s0022-3476(98)70153-2

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  12 in total

1.  Hypophosphatemia in Critically Ill Children: Risk Factors, Outcome and Mechanism.

Authors:  Satish Kumar Shah; Mohammad Irshad; Nandita Gupta; Sushil Kumar Kabra; Rakesh Lodha
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2.  Early hypophosphatemia in preterm infants receiving aggressive parenteral nutrition.

Authors:  P H Brener Dik; M F Galletti; S A Fernández Jonusas; G Alonso; G L Mariani; C A Fustiñana
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3.  Serum phosphate and magnesium in children recovering from severe acute undernutrition in Ethiopia: an observational study.

Authors:  Anne-Louise Hother; Tsinuel Girma; Maren J H Rytter; Alemseged Abdissa; Christian Ritz; Christian Mølgaard; Kim F Michaelsen; André Briend; Henrik Friis; Pernille Kæstel
Journal:  BMC Pediatr       Date:  2016-11-05       Impact factor: 2.125

4.  Metabolomic Changes in Serum of Children with Different Clinical Diagnoses of Malnutrition.

Authors:  Valeria Di Giovanni; Celine Bourdon; Dominic X Wang; Swapna Seshadri; Edward Senga; Christian J Versloot; Wieger Voskuijl; Richard D Semba; Indi Trehan; Ruin Moaddel; M Isabel Ordiz; Ling Zhang; John Parkinson; Mark J Manary; Robert Hj Bandsma
Journal:  J Nutr       Date:  2016-11-02       Impact factor: 4.798

5.  Corn-Soy-Blend Fortified with Phosphorus to Prevent Refeeding Hypophosphatemia in Undernourished Piglets.

Authors:  Anne-Louise Hother; Mikkel Lykke; Torben Martinussen; Hanne Damgaard Poulsen; Christian Mølgaard; Per Torp Sangild; André Briend; Christian Fink Hansen; Henrik Friis; Kim F Michaelsen; Thomas Thymann
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6.  Assessment of Myocardial Function in Kenyan Children With Severe, Acute Malnutrition: The Cardiac Physiology in Malnutrition (CAPMAL) Study.

Authors:  Bernadette Brent; Nchafatso Obonyo; Samuel Akech; Mohammed Shebbe; Ayub Mpoya; Neema Mturi; James A Berkley; Robert M R Tulloh; Kathryn Maitland
Journal:  JAMA Netw Open       Date:  2019-03-01

7.  Mortality risk among children admitted in a large-scale nutritional program in Niger, 2006.

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Journal:  PLoS One       Date:  2009-01-29       Impact factor: 3.240

8.  Risk factors in hospital deaths in severely malnourished children in Kampala, Uganda.

Authors:  Hanifa Bachou; James K Tumwine; Robert K N Mwadime; Thorkild Tylleskär
Journal:  BMC Pediatr       Date:  2006-03-16       Impact factor: 2.125

9.  Hypophosphataemia among severely-malnourished children: case series.

Authors:  Shoji Yoshimatsu; Mohammod Jobayer Chisti; Md Iqbal Hossain; Md Munirul Islam; Takashi Fukushima; Yukiko Wagatsuma; Jonathan Harvey Smith; Ryo Sumazaki; Tahmeed Ahmed
Journal:  J Health Popul Nutr       Date:  2012-12       Impact factor: 2.000

10.  Phosphate disturbance in critically ill children: Incidence, associated risk factors and clinical outcomes.

Authors:  Ahmed Nabih El Shazly; Doaa Refaey Soliman; Effat Hussien Assar; Eman Gamal Behiry; Ibrahim Abd El Naby Gad Ahmed
Journal:  Ann Med Surg (Lond)       Date:  2017-08-09
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