Literature DB >> 984041

Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh, Michigan. III. Identification of genetic effects using 12 polymorphic genetic blood marker systems.

C F Sing, J D Orr.   

Abstract

Four of 12 unlinked polymorphic marker systems were identified as predictors of normal serum cholesterol levels. Consistent effects between males and females and with other studies suggest that these marker loci are themselves involved in cholesterol determination or are closely linked to the involved loci. Two-locus combinations suggest that an 8-9 mg/100 ml difference in nonfasting serum cholesterol may be predicted between phenotypic classes which are not rare in frequency.

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Year:  1976        PMID： 984041      PMCID： PMC1685113     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  17 in total

1.  Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh, Michigan: II. The role of education, occupation, and income.

Authors:  J D Orr; C F Sing; W D Block
Journal:  Soc Biol       Date:  1975

Review 2.  Genetic markers in atherosclerosis: a review.

Authors:  N E Morton
Journal:  J Med Genet       Date:  1976-04       Impact factor: 6.318

3.  Serum-cholesterol and ABO and Lewis blood-groups.

Authors:  L Beckman; T Olivecrona
Journal:  Lancet       Date:  1970-05-09       Impact factor: 79.321

4.  Blood-groups and serum-cholesterol.

Authors: 
Journal:  Lancet       Date:  1969-09-20       Impact factor: 79.321

5.  ABO and Lewis blood-groups and serum-cholesterol.

Authors:  M J Langman; P C Elwood; J Foote; D R Ryrie
Journal:  Lancet       Date:  1969-09-20       Impact factor: 79.321

6.  A search for associations between genetical polymorphic systems and physical, biochemical and Haematological variables.

Authors:  G R Fraser; W S Volkers; L F Bernini; W B De Greve; E van Loghem; P Meera Khan; L E Nijenhuis; J J Veltkamp; G P Vogel; L N Went
Journal:  Hum Hered       Date:  1974       Impact factor: 0.444

7.  Blood groups and serum cholesterol among 10,000 adult males.

Authors:  J H Medalie; C Levene; C Papier; U Goldbourt; F Dreyfuss; D Oron; H Neufeld; E Riss
Journal:  Atherosclerosis       Date:  1971 Sep-Oct       Impact factor: 5.162

8.  Genetic influences on serum cholesterol in two Greek villages.

Authors:  O Mayo; G R Fraser; G Stamatoyannopoulos
Journal:  Hum Hered       Date:  1969       Impact factor: 0.444

9.  A relationship between plasma cholesterol level, latitude, and the Rhesus blood group system.

Authors:  B M Alfred; M Lee; I D Desai
Journal:  Hum Biol       Date:  1974-12       Impact factor: 0.553

10.  Studies on genetic selection in a completely ascertained caucasian population. I. Frequencies, age and sex effects, and phenotype associations for 12 blood group systems.

Authors:  D C Shreffler; C F Sing; J V Neel; H Gershowitz; J A Napier
Journal:  Am J Hum Genet       Date:  1971-03       Impact factor: 11.025
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  13 in total

Review 1.  Dissecting the genetic contribution to coronary heart disease.

Authors:  J W MacCluer; C M Kammerer
Journal:  Am J Hum Genet       Date:  1991-12       Impact factor: 11.025

2.  Rapid typing of tandemly repeated hypervariable loci by the polymerase chain reaction: application to the apolipoprotein B 3' hypervariable region.

Authors:  E Boerwinkle; W J Xiong; E Fourest; L Chan
Journal:  Proc Natl Acad Sci U S A       Date:  1989-01       Impact factor: 11.205

3.  Extended multipoint identity-by-descent analysis of human quantitative traits: efficiency, power, and modeling considerations.

Authors:  N J Schork
Journal:  Am J Hum Genet       Date:  1993-12       Impact factor: 11.025

4.  The contribution of quantitative trait loci and neutral marker loci to the genetic variances and covariances among quantitative traits in random mating populations.

Authors:  A Ruiz; A Barbadilla
Journal:  Genetics       Date:  1995-01       Impact factor: 4.562

Review 5.  A defense of path analysis in genetic epidemiology.

Authors:  C R Cloninger; D C Rao; J Rice; T Reich; N E Morton
Journal:  Am J Hum Genet       Date:  1983-07       Impact factor: 11.025

6.  Detection of genetic heterogeneity among pedigrees through complex segregation analysis: an application to hypercholesterolemia.

Authors:  P P Moll; T D Berry; W H Weidman; R Ellefson; H Gordon; B A Kottke
Journal:  Am J Hum Genet       Date:  1984-01       Impact factor: 11.025

7.  Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh, Michigan. IV. Separation of polygene from common environment effects.

Authors:  C F Sing; J D Orr
Journal:  Am J Hum Genet       Date:  1978-09       Impact factor: 11.025

8.  The gender-specific apolipoprotein E genotype influence on the distribution of lipids and apolipoproteins in the population of Rochester, MN. I. Pleiotropic effects on means and variances.

Authors:  S L Reilly; R E Ferrell; B A Kottke; M I Kamboh; C F Sing
Journal:  Am J Hum Genet       Date:  1991-12       Impact factor: 11.025

9.  The gender-specific apolipoprotein E genotype influence on the distribution of plasma lipids and apolipoproteins in the population of Rochester, MN. III. Correlations and covariances.

Authors:  S L Reilly; R E Ferrell; C F Sing
Journal:  Am J Hum Genet       Date:  1994-11       Impact factor: 11.025

10.  Patterns of association between genetic variability in apolipoprotein (apo) B, apo AI-CIII-AIV, and cholesterol ester transfer protein gene regions and quantitative variation in lipid and lipoprotein traits: influence of gender and exogenous hormones.

Authors:  A Kessling; S Ouellette; O Bouffard; A Chamberland; C Bétard; E Selinger; M Xhignesse; S Lussier-Cacan; J Davignon
Journal:  Am J Hum Genet       Date:  1992-01       Impact factor: 11.025
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