Literature DB >> 9839626

Hyaluronidase as additive to induction chemotherapy in advanced squamous cell carcinoma of the head and neck.

J Klocker1, H Sabitzer, W Raunik, S Wieser, J Schumer.   

Abstract

Forty-eight patients with advanced head and neck tumours were treated with irradiation and concomitant chemotherapy with cisplatin, vindesine and hyaluronidase. The disease-free survival rate at 5 years was 47%. The toxic effects were mucositis (48 patients), nausea (25 patients, vomiting in six patients), bone marrow depression (15 patients) and peripheral neuropathy (14 patients). The results warrant a randomized trial.

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Year:  1998        PMID: 9839626     DOI: 10.1016/s0304-3835(98)00207-9

Source DB:  PubMed          Journal:  Cancer Lett        ISSN: 0304-3835            Impact factor:   8.679


  9 in total

1.  Targeting the tumor microenvironment in cancer: why hyaluronidase deserves a second look.

Authors:  Clifford J Whatcott; Haiyong Han; Richard G Posner; Galen Hostetter; Daniel D Von Hoff
Journal:  Cancer Discov       Date:  2011-09       Impact factor: 39.397

2.  Lifetime-based sensing of the hyaluronidase using fluorescein labeled hyaluronic acid.

Authors:  Rafal Fudala; Mark E Mummert; Zygmunt Gryczynski; Ryan Rich; Julian Borejdo; Ignacy Gryczynski
Journal:  J Photochem Photobiol B       Date:  2011-10-20       Impact factor: 6.252

Review 3.  Hyalurondiase: both a tumor promoter and suppressor.

Authors:  Vinata B Lokeshwar; Marie G Selzer
Journal:  Semin Cancer Biol       Date:  2008-03-26       Impact factor: 15.707

Review 4.  Hyaluronan and hyaluronidase in genitourinary tumors.

Authors:  Melanie A Simpson; Vinata B Lokeshwar
Journal:  Front Biosci       Date:  2008-05-01

Review 5.  Mounting Pressure in the Microenvironment: Fluids, Solids, and Cells in Pancreatic Ductal Adenocarcinoma.

Authors:  Christopher C DuFort; Kathleen E DelGiorno; Sunil R Hingorani
Journal:  Gastroenterology       Date:  2016-04-09       Impact factor: 22.682

Review 6.  Breaching the Castle Walls: Hyaluronan Depletion as a Therapeutic Approach to Cancer Therapy.

Authors:  H Michael Shepard
Journal:  Front Oncol       Date:  2015-08-28       Impact factor: 6.244

Review 7.  Utilization of Glycosaminoglycans/Proteoglycans as Carriers for Targeted Therapy Delivery.

Authors:  Suniti Misra; Vincent C Hascall; Ilia Atanelishvili; Ricardo Moreno Rodriguez; Roger R Markwald; Shibnath Ghatak
Journal:  Int J Cell Biol       Date:  2015-09-10

8.  Therapeutic targeting of hyaluronan in the tumor stroma.

Authors:  Anne Kultti; Xiaoming Li; Ping Jiang; Curtis B Thompson; Gregory I Frost; H Michael Shepard
Journal:  Cancers (Basel)       Date:  2012-09-06       Impact factor: 6.639

9.  Arthropod venom Hyaluronidases: biochemical properties and potential applications in medicine and biotechnology.

Authors:  Karla C F Bordon; Gisele A Wiezel; Fernanda G Amorim; Eliane C Arantes
Journal:  J Venom Anim Toxins Incl Trop Dis       Date:  2015-10-22
  9 in total

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