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Literature DB >> 9836465

Evaluation of anti-HIV activity of 5-(2-phenyl-3'-indolal)-2-thiohydantoin.

Abstract

The anti-HIV activity of the previously synthesized 5-(2-phenyl-3'-indolal)-2-thiohydantoin I was evaluated. The compound, containing two structural moieties found in highly active anti-HIV agents, exhibited poor activity and rather high cytotoxicity.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1998 PMID： 9836465 DOI： 10.1016/s0014-827x(98)00053-6

Source DB: PubMed Journal: Farmaco ISSN： 0014-827X

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Cited

8 in total

1. Cytotoxic activities and DNA binding properties of 1-methyl-7H-indeno[1,2-b]quinolinium-7-(4-dimethylamino) benzylidene triflate.

Authors: Wen Li; Yuan Yuan Ji; Jian Wen Wang; Yong Ming Zhu
Journal: DNA Cell Biol Date: 2012-01-25 Impact factor: 3.311

Review 2. The Molecular Diversity of 1H-Indole-3-Carbaldehyde Derivatives and Their Role in Multicomponent Reactions.

Authors: Ghodsi Mohammadi Ziarani; Samira Hasani; Fatemeh Mohajer; Rajender S Varma; Fatemeh Rafiee
Journal: Top Curr Chem (Cham) Date: 2022-04-25

Review 3. Recent developments in green approaches for sustainable synthesis of indole-derived scaffolds.

Authors: Shima Nasri; Mohammad Bayat; Fatemeh Rostami Miankooshki; Narges Habibi Samet
Journal: Mol Divers Date: 2022-01-15 Impact factor: 2.943

4. Isolation and Structural Elucidation of Compounds from Pleiocarpa bicarpellata and Their In Vitro Antiprotozoal Activity.

Authors: Ozlem Sevik Kilicaslan; Sylvian Cretton; Luis Quirós-Guerrero; Merveilles A Bella; Marcel Kaiser; Pascal Mäser; Joseph T Ndongo; Muriel Cuendet
Journal: Molecules Date: 2022-03-28 Impact factor: 4.411

Evaluation of anti-HIV activity of 5-(2-phenyl-3'-indolal)-2-thiohydantoin.

1. Cytotoxic activities and DNA binding properties of 1-methyl-7H-indeno[1,2-b]quinolinium-7-(4-dimethylamino) benzylidene triflate.

Review 2. The Molecular Diversity of 1H-Indole-3-Carbaldehyde Derivatives and Their Role in Multicomponent Reactions.

Review 3. Recent developments in green approaches for sustainable synthesis of indole-derived scaffolds.

4. Isolation and Structural Elucidation of Compounds from Pleiocarpa bicarpellata and Their In Vitro Antiprotozoal Activity.

5. Synthesis and cytotoxic evaluation of novel 3-substituted derivatives of 2-indolinone.

6. Novel indole-based analogs of melatonin: synthesis and in vitro antioxidant activity studies.

7. An Efficient Synthesis of Acenaphtho[1,2-b]indole Derivatives via Domino Reaction.

Review 8. Nitroketene N,S-acetals: synergistic building blocks for the synthesis of heterocycles.